Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17787488 | 0.88 | DPP7 (0.35) | KMT2AMEN1POLBTOP2ATP53 | |
| SCHEMBL17787481 | 0.81 | MGLL (0.41) | TP53MAPTPTGS1PTGS2ALDH1A1 | |
| SCHEMBL14772133 | 0.79 | PTGS1 (0.36) | KMT2AMEN1POLBTP53MAPT | |
| SCHEMBL17787489 | 0.78 | SIRT2 (0.32) | — | |
| SCHEMBL12680360 | 0.76 | TP53 (0.40) | TP53MAPTOPRM1OPRD1OPRK1 | |
| SCHEMBL15613431 | 0.74 | PTGS1 (0.57) | TP53PTGS1PTGS2DNM1 | |
| SCHEMBL12107717 | 0.74 | PTGS1 (0.51) | POLBTP53MAPTPTGS1PTGS2 | |
| SCHEMBL15739654 | 0.73 | PTGS1 (0.60) | TP53PTGS1PTGS2DNM1 | |
| SCHEMBL12642012 | 0.73 | PTGS1 (0.54) | TP53MAPTPTGS1PTGS2ALDH1A1 | |
| SCHEMBL13828057 | 0.73 | PTGS1 (0.46) | KMT2AMEN1TP53MAPTPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9487480-B2 | Zwitterionic reagents | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2016-11-08 | — | — | US | disclosed |
| US-9353056-B2 | — | — | 2016-05-31 | — | — | US | disclosed |