Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.35 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.34 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.34 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
| ▸ | TERT | O14746 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TLR2 | O60603 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TOP2A | P11388 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RRM1 | P23921 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17787484 | 0.88 | KMT2A (0.38) | OPRM1OPRD1OPRK1MEN1KMT2A | |
| SCHEMBL17787489 | 0.79 | SIRT2 (0.32) | — | |
| SCHEMBL10071026 | 0.78 | DPP7 (0.42) | DPP7GNAI3GNAO1GNAI1OPRM1 | |
| SCHEMBL18088319 | 0.78 | FOLH1 (0.42) | — | |
| SCHEMBL462896 | 0.78 | GNAI3 (0.43) | DPP7GNAI3GNAO1GNAI1OPRM1 | |
| SCHEMBL27636331 | 0.76 | TDP1 (0.47) | OPRM1OPRD1OPRK1MEN1KMT2A | |
| SCHEMBL11990337 | 0.72 | MAPT (0.45) | OPRM1OPRD1OPRK1MEN1KMT2A | |
| SCHEMBL28558143 | 0.72 | TERT (0.49) | DPP7GNAI3GNAO1GNAI1TERT | |
| SCHEMBL31722070 | 0.72 | PTGS1 (0.50) | OPRM1OPRD1OPRK1MEN1KMT2A | |
| SCHEMBL30202393 | 0.72 | PTGS1 (0.50) | OPRM1OPRD1OPRK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9487480-B2 | Zwitterionic reagents | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2016-11-08 | — | — | US | disclosed |
| US-20160274094-A1 | ZWITTERIONIC REAGENTS | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2016-09-22 | — | — | US | disclosed |
| US-9353056-B2 | — | — | 2016-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160274094-A1 | ZWITTERIONIC REAGENTS | BTD, HLCS, WIZ | DPP7 1515/4885GNAI3 2851/4885GNAO1 3969/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.