SCHEMBL1778770

SCHEMBL1778770

C=C(C)C(=O)OC(C)NS(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.51

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA1 P00915 7/20 0.51
CA2 P00918 7/20 0.51
MMP1 P03956 7/20 0.51
MMP2 P08253 7/20 0.51
MMP9 P14780 7/20 0.51
MMP8 P22894 7/20 0.51
MMP13 P45452 7/20 0.51
F2 P00734 2/20 0.34
PRSS1 P07477 2/20 0.34
PRSS2 P07478 2/20 0.34
PRSS3 P35030 2/20 0.34
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3820635 0.99 CA2 (0.50) CA1CA2MMP1MMP2MMP9
SCHEMBL7615808 0.96 CA1 (0.46) CA1CA2MMP1MMP2MMP9
SCHEMBL3459499 0.89 CA1 (0.38) CA1CA2MMP1MMP2MMP9
SCHEMBL8209700 0.87 CA1 (0.38) CA1CA2MMP1MMP2MMP9
SCHEMBL9237821 0.84 CA1 (0.35) CA1CA2MMP1MMP2MMP9
SCHEMBL10064117 0.83 ALDH1A1 (0.36) CA1CA2MMP1MMP2MMP9
SCHEMBL11862221 0.80 CA1 (0.43) CA1CA2MMP1MMP2MMP9
SCHEMBL325042 0.80 CA1 (0.51) CA1CA2MMP1MMP2MMP9
SCHEMBL28384329 0.79 CA2 (0.50) CA1CA2MMP1MMP2MMP9
SCHEMBL5399537 0.79 CA2 (0.50) CA1CA2MMP1MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6894105-B2 Dyed fluoropolymers 3M INNOVATIVES PROPERTIES COMPANY (US) 2005-05-17 US claimed
EP-1525240-A1 DYED FLUOROPOLYMERS 3M Innovative Properties Company (US) 2005-04-27 EP claimed
WO-2004011512-A1 DYED FLUOROPOLYMERS 3M INNOVATIVE PROPERTIES COMPANY (US) 2004-02-05 WO claimed
US-20040024100-A1 Dyed fluoropolymers 3M INNOVATIVE PROPERTIES COMPANY 2004-02-05 US claimed
EP-1699790-B1 SOLUBLE POLYMERS AS AMINE CAPTURE AGENTS AND METHODS 3M INNOVATIVE PROPERTIES CO (US) 2012-09-05 EP disclosed
EP-1700107-B1 ACOUSTIC SENSORS AND METHODS 3M INNOVATIVE PROPERTIES CO (US) 2011-09-14 EP disclosed
US-7943388-B2 Acoustic sensors and methods 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-05-17 US disclosed
US-7521516-B2 pendant acylsulfonamide amine-reactive groups; for covalent attachment of amine-containing analytes, amino acids, DNA fragments, RNA fragments, protein fragments, organelles, and immunoglobins, immobilized on the surface of a substrate 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-04-21 US disclosed
US-20080132665-A1 SOLUBLE POLYMERS AS AMINE CAPTURE AGENTS AND METHODS BENSON KARL E 2008-06-05 US disclosed
US-7342082-B2 Soluble polymers as amine capture agents and methods 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-03-11 US disclosed
US-20070190662-A1 Acoustic sensors and methods 3M INNOVATIVE PROPERTIES COMPANY 2007-08-16 US disclosed
WO-2005066092-A9 ACOUSTIC SENSORS AND METHODS 3M INNOVATIVE PROPERTIES CO (US) 2006-09-14 WO disclosed
WO-2005065370-A2 SOLUBLE POLYMERS AS AMINE CAPTURE AGENTS AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2005-07-21 WO disclosed
US-6894105-B2 Dyed fluoropolymers 3M INNOVATIVES PROPERTIES COMPANY (US) 2005-05-17 US disclosed
EP-1525240-A1 DYED FLUOROPOLYMERS 3M Innovative Properties Company (US) 2005-04-27 EP disclosed
EP-1525268-A1 FUNCTIONAL FLUORESCENT DYES 3M Innovative Properties Company (US) 2005-04-27 EP disclosed
WO-2004011512-A1 DYED FLUOROPOLYMERS 3M INNOVATIVE PROPERTIES COMPANY (US) 2004-02-05 WO disclosed
WO-2004011557-A1 FUNCTIONAL FLUORESCENT DYES 3M INNOVATIVE PROPERTIES COMPANY (US) 2004-02-05 WO disclosed
US-20040024100-A1 Dyed fluoropolymers 3M INNOVATIVE PROPERTIES COMPANY 2004-02-05 US disclosed
US-20040016370-A1 Functional fluorescent dyes 3M INNOVATIVE PROPERTIES COMPANY 2004-01-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040016370-A1 Functional fluorescent dyes ARL1, HACL2, GLB1 CA1 4237/4885CA2 2671/4885MMP1 4569/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.