Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17791688 | 0.90 | LMNA (0.38) | ALDH1A1LMNAPOLBUSP2SMN1; SMN2 | |
| SCHEMBL17791684 | 0.88 | ALDH1A1 (0.31) | ALDH1A1TDP1 | |
| SCHEMBL17791689 | 0.78 | ALDH1A1 (0.39) | ALDH1A1LMNAPOLBUSP2SMN1; SMN2 | |
| SCHEMBL12989914 | 0.70 | ATM (0.33) | — | |
| SCHEMBL21727736 | 0.69 | CHRM2 (0.32) | — | |
| SCHEMBL20776509 | 0.69 | CHRM2 (0.32) | — | |
| SCHEMBL20776443 | 0.69 | CHRM2 (0.32) | — | |
| SCHEMBL21281750 | 0.69 | — | — | |
| SCHEMBL4330147 | 0.68 | — | — | |
| SCHEMBL584063 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9359376-B2 | Substituted methylformyl reagents and method of using same to modify physicochemical and/or pharmacokinetic properties of compounds | SPHAERA PHARMA PTE. LTD (SG) | 2016-06-07 | — | — | US | claimed |