Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | MMP1 | P03956 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17793727 | 0.90 | LMNA (0.51) | LMNACYP19A1KMT2AMEN1CA1 | |
| SCHEMBL17793725 | 0.90 | ALDH1A1 (0.54) | LMNACYP19A1KMT2AMEN1CA1 | |
| SCHEMBL17793730 | 0.88 | ALDH1A1 (0.49) | LMNACYP19A1KMT2AMEN1CA1 | |
| SCHEMBL6925091 | 0.84 | CA1 (0.56) | LMNACYP19A1KMT2AMEN1CA1 | |
| SCHEMBL28897943 | 0.82 | CA1 (0.54) | LMNACYP19A1KMT2AMEN1CA1 | |
| SCHEMBL28897944 | 0.82 | CA1 (0.54) | LMNACYP19A1KMT2AMEN1CA1 | |
| SCHEMBL1548112 | 0.80 | ALDH1A1 (0.60) | LMNACYP19A1KMT2AMEN1CA1 | |
| SCHEMBL25353698 | 0.80 | CA1 (0.51) | LMNACYP19A1KMT2AMEN1CA1 | |
| SCHEMBL17793719 | 0.80 | KMT2A (0.58) | LMNACYP19A1KMT2AMEN1CA1 | |
| SCHEMBL25353051 | 0.78 | CA1 (0.52) | LMNACYP19A1KMT2AMEN1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016082052-A1 | COMPOUNDS DERIVED FROM 2-PHENYL-2-FLUOROSULFONAMIDES, USED AS BUILDING BLOCKS IN ORGANIC SYNTHESIS, AND METHOD FOR THE PRODUCTION THEREOF | PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE (CL) | 2016-06-02 | — | — | WO | disclosed |