Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15244291 | 0.86 | BCHE (0.34) | ALDH1A1BCHEHSD17B10 | |
| SCHEMBL17796551 | 0.82 | KDM4E (0.31) | KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL17796523 | 0.80 | CTSB (0.45) | KDM4EALDH1A1L3MBTL1HSD17B10NR4A1 | |
| SCHEMBL16446409 | 0.79 | — | — | |
| SCHEMBL17796385 | 0.78 | KDM4E (0.38) | KDM4EALDH1A1L3MBTL1PDE10A | |
| SCHEMBL17796471 | 0.77 | SETDB1 (0.40) | KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL6125259 | 0.77 | BAZ2B (0.37) | KDM4EALDH1A1L3MBTL1BCHEBRD9 | |
| SCHEMBL17796730 | 0.74 | — | — | |
| SCHEMBL243532 | 0.72 | — | — | |
| SCHEMBL1064764 | 0.72 | KDM4E (0.33) | KDM4EALDH1A1L3MBTL1NR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160159773-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-06-09 | — | — | US | disclosed |
| EP-3029031-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2016-06-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160159773-A1 | HETEROCYCLIC COMPOUND | TYK2, SSB, UACA | KDM4E 1049/4885ALDH1A1 4734/4885L3MBTL1 4586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.