Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17797151 | 0.87 | ABCG2 (0.35) | ABCG2HTR2AMAPTMEN1KMT2A | |
| SCHEMBL17797149 | 0.83 | AHR (0.37) | ABCG2MAPTMEN1KMT2APOLB | |
| SCHEMBL2635017 | 0.79 | HNF4A (0.40) | ABCG2MAPTMEN1KMT2APOLB | |
| SCHEMBL12588930 | 0.74 | KMT2A (0.34) | MAPTKMT2AALDH1A1NPSR1KDM4E | |
| SCHEMBL18723236 | 0.69 | ABCG2 (0.36) | ABCG2HTR2AMAPTMEN1KMT2A | |
| SCHEMBL11988006 | 0.69 | ALDH1A1 (0.35) | ABCG2MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13937577 | 0.67 | ABCG2 (0.47) | ABCG2MAPTMEN1KMT2APOLB | |
| SCHEMBL16676467 | 0.67 | KMT2A (0.50) | ABCG2MAPTMEN1KMT2APOLB | |
| SCHEMBL17797143 | 0.64 | ABCG2 (0.35) | ABCG2MAPTMEN1KMT2APOLB | |
| SCHEMBL18826298 | 0.64 | CYP1A2 (0.36) | ABCG2MAPTMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029054-B1 | Phosphoramidites containing a phenyl-phenyl unit or a phenyl-naphthyl unit | EVONIK DEGUSSA GMBH (DE) | 2016-11-23 | — | — | EP | disclosed |
| EP-3037427-B1 | MONOPHOSPHITES WITH A NAPHTHOL | EVONIK DEGUSSA GMBH (DE) | 2016-11-23 | — | — | EP | disclosed |
| EP-3037427-A1 | MONOPHOSPHITES WITH A NAPHTHOL | Evonik Degussa GmbH (DE) | 2016-06-29 | — | — | EP | disclosed |
| EP-3029053-A1 | Monophosphites with a naphthol | Evonik Degussa GmbH (DE) | 2016-06-08 | — | — | EP | disclosed |
| EP-3029054-A1 | Phosphoramidites containing a phenyl-phenyl unit or a phenyl-naphthyl unit | Evonik Degussa GmbH (DE) | 2016-06-08 | — | — | EP | disclosed |