Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KHK | P50053 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2470881 | 0.91 | MAPK8 (0.36) | HPGDKDM4EALDH1A1MAPTKHK | |
| SCHEMBL2471013 | 0.87 | TPMT (0.32) | KDM4EALDH1A1GAA | |
| SCHEMBL3836857 | 0.86 | HPGD (0.35) | HPGDKHKMAPK8MAPK9 | |
| SCHEMBL2468291 | 0.85 | ILK (0.30) | — | |
| SCHEMBL17797245 | 0.85 | ALDH1A1 (0.35) | HPGDKDM4EALDH1A1MAPTLMNA | |
| SCHEMBL17797250 | 0.85 | HSD17B10 (0.33) | HTT | |
| SCHEMBL3333426 | 0.83 | KHK (0.36) | HPGDKDM4EALDH1A1MAPTKHK | |
| SCHEMBL17797241 | 0.81 | TPMT (0.32) | KDM4EALDH1A1GAA | |
| SCHEMBL2464658 | 0.78 | KDM4E (0.33) | KDM4EALDH1A1MAPK8MAPK9GAA | |
| SCHEMBL2467726 | 0.78 | PDCD1LG2 (0.31) | MAPK8MAPK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2060566-B1 | Poly-substituted aryls | DOW AGROSCIENCES LLC (US) | 2016-06-08 | — | — | EP | claimed |