Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 3/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 13/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SHBG | P04278 | 2/20 | 0.43 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.43 |
| ▸ | SNCA | P37840 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1780129 | 1.00 | CYP17A1 (0.55) | CYP17A1CYP19A1ALDH1A1KDM4EABCB11 | |
| SCHEMBL1900489 | 0.88 | CYP19A1 (0.70) | CYP19A1ALDH1A1NR3C1PGRMAPK1 | |
| SCHEMBL1900487 | 0.88 | CYP19A1 (0.70) | CYP19A1ALDH1A1NR3C1PGRMAPK1 | |
| SCHEMBL349056 | 0.84 | CYP19A1 (0.76) | CYP17A1CYP19A1ALDH1A1KDM4EABCB11 | |
| SCHEMBL10187417 | 0.84 | CYP19A1 (0.76) | CYP17A1CYP19A1ALDH1A1KDM4EABCB11 | |
| SCHEMBL349057 | 0.84 | CYP19A1 (0.76) | CYP17A1CYP19A1ALDH1A1KDM4EABCB11 | |
| SCHEMBL8980421 | 0.84 | CYP19A1 (0.54) | CYP17A1CYP19A1ALDH1A1KDM4EABCB11 | |
| SCHEMBL8980429 | 0.84 | CYP19A1 (0.54) | CYP17A1CYP19A1ALDH1A1KDM4EABCB11 | |
| SCHEMBL10380895 | 0.84 | CYP19A1 (0.72) | CYP17A1CYP19A1ALDH1A1NR3C1PGR | |
| SCHEMBL10380893 | 0.84 | CYP19A1 (0.72) | CYP17A1CYP19A1ALDH1A1NR3C1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110118488-A1 | PROCESS FOR OBTAINING 6-ALKYLIDENANDROST-1, 4-DIENE-3-ONE | CRYSTAL PHARMA, S.A. (ES) | 2011-05-19 | — | — | US | disclosed |
| WO-2009077454-A1 | PROCESS FOR OBTAINING 6-ALKYLIDENANDROST-1, 4-DIENE-3-ONE | CRYSTAL PHARMA, S.A. (ES) | 2009-06-25 | — | — | WO | disclosed |
| EP-2070943-A1 | Process for obtaining 6-Alkylidenandrost-1,4-diene-3one | Crystal Pharma, S.A. (ES) | 2009-06-17 | — | — | EP | disclosed |
| US-5227375-A | Androstanediones, estrogen-dependent diseases, anticancer | ENDORECHERCHE, INC. (CA) | 1993-07-13 | — | — | US | disclosed |
| EP-0307135-B1 | 17-SUBSTITUTED ANDROSTA-1,4-DIEN-3-ONE DERIVATIVES | FARMITALIA CARLO ERBA S.r.l. (IT) | 1992-08-19 | — | — | EP | disclosed |
| WO-1991012206-A2 | AROMATASE-INHIBITING STEROIDS | ENDORECHERCHE INC. (CA) | 1991-08-22 | — | — | WO | disclosed |
| US-3953483-A | ANTI-ANDROGENIC | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1976-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118488-A1 | PROCESS FOR OBTAINING 6-ALKYLIDENANDROST-1, 4-DIENE-3-ONE | SRD5A1, SRD5A2, NR5A1 | CYP17A1 4/4885CYP19A1 6/4885ALDH1A1 120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.