Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 15/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.66 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.66 |
| ▸ | PGR | P06401 | 1/20 | 0.66 |
| ▸ | HTR2A | P28223 | 1/20 | 0.66 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.66 |
| ▸ | HTR2B | P41595 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | SHBG | P04278 | 2/20 | 0.61 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.61 |
| ▸ | SNCA | P37840 | 2/20 | 0.61 |
| ▸ | BLM | P54132 | 2/20 | 0.61 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL349057 | 1.00 | CYP19A1 (0.76) | CYP19A1ALDH1A1KDM4EABCB11NR3C1 | |
| SCHEMBL10187417 | 1.00 | CYP19A1 (0.76) | CYP19A1ALDH1A1KDM4EABCB11NR3C1 | |
| SCHEMBL10603696 | 0.87 | CYP19A1 (0.58) | CYP19A1ALDH1A1KDM4EABCB11NR3C1 | |
| SCHEMBL42713 | 0.86 | CYP19A1 (1.00) | CYP19A1ALDH1A1LMNASHBGSERPINA6 | |
| SCHEMBL42712 | 0.86 | CYP19A1 (1.00) | CYP19A1ALDH1A1LMNASHBGSERPINA6 | |
| SCHEMBL2600419 | 0.86 | CYP19A1 (1.00) | CYP19A1ALDH1A1LMNASHBGSERPINA6 | |
| SCHEMBL3275185 | 0.85 | CYP19A1 (0.78) | CYP19A1ALDH1A1LMNASHBGSERPINA6 | |
| SCHEMBL8980388 | 0.85 | CYP19A1 (0.55) | CYP19A1ALDH1A1KDM4EABCB11NR3C1 | |
| SCHEMBL8980383 | 0.85 | CYP19A1 (0.55) | CYP19A1ALDH1A1KDM4EABCB11NR3C1 | |
| SCHEMBL1780130 | 0.84 | CYP17A1 (0.55) | CYP19A1ALDH1A1KDM4EABCB11NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119409756-A | Rigid spiro compound and preparation method and application thereof | 绍兴文理学院 | 2025-02-11 | — | — | CN | claimed |
| CN-117051415-A | Preparation method of exemestane | 台州学院 | 2023-11-14 | — | — | CN | claimed |
| CN-112409432-B | Synthesis method of exemestane | 陕西理工大学 | 2023-07-07 | — | — | CN | claimed |
| CN-112409432-A | Synthesis method of exemestane | 陕西理工大学 | 2021-02-26 | — | — | CN | claimed |
| WO-2010076811-A2 | PROCESS FOR THE PREPARATION OF EXEMESTANE | IND-SWIFT LABORATORIES LIMITED (IN) | 2010-07-08 | — | — | WO | claimed |
| WO-2001004342-A1 | PROCESS TO PREPARE EXEMESTANE | PHARMACIA & UPJOHN COMPANY (US) | 2001-01-18 | — | — | WO | claimed |
| CN-119409756-A | Rigid spiro compound and preparation method and application thereof | 绍兴文理学院 | 2025-02-11 | — | — | CN | disclosed |
| US-20240238310-A1 | MODULATION OF SEX STEROID HORMONE PRODUCTION AND ACTIVITY FOR TREATING AND PREVENTING HERNIAS | NORTHWESTERN UNIVERSITY | 2024-07-18 | — | — | US | disclosed |
| CN-111808011-B | High penetration composition and its application | 泰飞尔生物医药(苏州)有限公司 | 2024-02-27 | — | — | CN | disclosed |
| CN-117070482-A | 3-sterone-1, 2-dehydrogenase mutant, coding gene, vector and application | 黄冈人福药业有限责任公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-117070482-A | 3-sterone-1, 2-dehydrogenase mutant, coding gene, vector and application | 黄冈人福药业有限责任公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-117051415-A | Preparation method of exemestane | 台州学院 | 2023-11-14 | — | — | CN | disclosed |
| CN-117051415-A | Preparation method of exemestane | 台州学院 | 2023-11-14 | — | — | CN | disclosed |
| US-4567001-A | 16-Methylene-17α-hydroxy-progesterones | THE UPJOHN COMPANY (US) | 1986-01-28 | — | — | US | disclosed |
| EP-0148616-A2 | Stabilised monolithium acetylide and the ethynylation of steroids | THE UPJOHN COMPANY (US) | 1985-07-17 | — | — | EP | disclosed |
| US-4526720-A | Process to prepare stabilized monolithium acetylide | THE UPJOHN COMPANY (US) | 1985-07-02 | — | — | US | disclosed |
| EP-0104054-A2 | 16-methylene-steroids and their preparation | THE UPJOHN COMPANY (US) | 1984-03-28 | — | — | EP | disclosed |
| EP-0034115-B1 | PROCESS FOR THE PREPARATION OF 6-METHYLENE STEROIDS | SCHERING AKTIENGESELLSCHAFT (DE) | 1983-06-08 | — | — | EP | disclosed |
| US-4322349-A | Process for preparing 6-methylene steroids | SCHERING AKTIENGESELLSCHAFT (DE) | 1982-03-30 | — | — | US | disclosed |
| EP-0034115-A2 | Process for the preparation of 6-methylene steroids | SCHERING AKTIENGESELLSCHAFT (DE) | 1981-08-19 | — | — | EP | disclosed |