Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 13/20 | 0.54 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | SHBG | P04278 | 2/20 | 0.43 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.43 |
| ▸ | SNCA | P37840 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8980421 | 1.00 | CYP19A1 (0.54) | CYP19A1CYP17A1LMNAHTTALDH1A1 | |
| SCHEMBL8759457 | 0.88 | CYP19A1 (0.70) | CYP19A1LMNAALDH1A1SHBGSERPINA6 | |
| SCHEMBL8759450 | 0.88 | CYP19A1 (0.70) | CYP19A1LMNAALDH1A1SHBGSERPINA6 | |
| SCHEMBL1780129 | 0.84 | CYP17A1 (0.55) | CYP19A1CYP17A1LMNAHTTALDH1A1 | |
| SCHEMBL1780130 | 0.84 | CYP17A1 (0.55) | CYP19A1CYP17A1LMNAHTTALDH1A1 | |
| SCHEMBL10187417 | 0.84 | CYP19A1 (0.76) | CYP19A1CYP17A1LMNAALDH1A1KDM4E | |
| SCHEMBL349056 | 0.84 | CYP19A1 (0.76) | CYP19A1CYP17A1LMNAALDH1A1KDM4E | |
| SCHEMBL349057 | 0.84 | CYP19A1 (0.76) | CYP19A1CYP17A1LMNAALDH1A1KDM4E | |
| SCHEMBL8980388 | 0.82 | CYP19A1 (0.55) | CYP19A1CYP17A1LMNAHTTALDH1A1 | |
| SCHEMBL8980383 | 0.82 | CYP19A1 (0.55) | CYP19A1CYP17A1LMNAHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5519051-A | AROMATASE INHIBITORS USEFUL FOR TREATMENT OF DISEASES CAUSED BY EXCESS OF ESTROGEN, FOR EXAMPLE, BREAST CANCER, UTERINE CANCER | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1996-05-21 | — | — | US | disclosed |
| EP-0582713-A1 | NOVEL OXA- OR AZASTEROID DERIVATIVE | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1994-02-16 | — | — | EP | disclosed |