SCHEMBL17801673

SCHEMBL17801673

O=C(OC[C@H]1CN(c2ccc(I)c(F)c2)C(=O)O1)OC[C@H]1CN(c2ccc(I)c(F)c2)C(=O)O1

nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAOA P21397 6/20 0.48
CALML3 P27482 7/20 0.48
MAOB P27338 5/20 0.48
LMNA P02545 1/20 0.48
PTGS1 P23219 1/20 0.48
SDHA P31040 1/20 0.48
F10 P00742 1/20 0.44
GRM2 Q14416 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17801674 0.92 MAOA (0.48) MAOACALML3MAOBLMNAPTGS1
SCHEMBL3370435 0.91 MAOA (0.49) MAOACALML3MAOBLMNAPTGS1
SCHEMBL3328728 0.91 MAOA (0.49) MAOACALML3MAOBLMNAPTGS1
SCHEMBL17811402 0.86 CALML3 (0.47) MAOACALML3MAOBLMNAPTGS1
SCHEMBL1035579 0.84 CALML3 (0.65) MAOACALML3MAOBLMNAPTGS1
SCHEMBL1557322 0.84 CALML3 (0.65) MAOACALML3MAOBLMNAPTGS1
SCHEMBL1032547 0.82 MAOB (0.48) MAOACALML3MAOBLMNAPTGS1
SCHEMBL1033024 0.82 MAOA (0.70) MAOACALML3MAOBLMNAPTGS1
SCHEMBL1032546 0.82 MAOB (0.48) MAOACALML3MAOBLMNAPTGS1
SCHEMBL1033023 0.82 MAOA (0.70) MAOACALML3MAOBLMNAPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016088103-A1 A PROCESS FOR THE PREPARATION OF TEDIZOLID PHOSPHATE SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) 2016-06-09 WO disclosed
WO-2016088102-A1 PROCESSES FOR THE PREPARATION OF TEDIZOLID PHOSPHATE AND ITS INTERMEDIATES SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) 2016-06-09 WO disclosed
WO-2016088101-A1 PROCESSES FOR THE PREPARATION OF TEDIZOLID PHOSPHATE AND ITS INTERMEDIATES SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) 2016-06-09 WO disclosed
WO-2016088100-A1 PROCESSES FOR THE PREPARATION OF TEDIZOLID PHOSPHATE AND ITS INTERMEDIATES SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) 2016-06-09 WO disclosed