Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.46 |
| ▸ | SCD | O00767 | 2/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.45 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.45 |
| ▸ | PI4KA | P42356 | 1/20 | 0.45 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17801688 | 0.82 | KDM4E (0.74) | NPC1RAB9ASMN1; SMN2KDM4ELMNA | |
| SCHEMBL30421174 | 0.82 | APP (0.61) | NPC1RAB9AGLAGAA | |
| SCHEMBL17801310 | 0.82 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2KDM4ELMNA | |
| SCHEMBL17801744 | 0.82 | APP (0.49) | NPC1RAB9ASMN1; SMN2KDM4ELMNA | |
| SCHEMBL30420821 | 0.78 | RAB9A (0.66) | NPC1RAB9ASMN1; SMN2LMNANFKB1 | |
| SCHEMBL28175321 | 0.77 | NPC1 (0.64) | NPC1RAB9ASMN1; SMN2KDM4ELMNA | |
| SCHEMBL17803457 | 0.77 | NPC1 (0.47) | NPC1RAB9AKDM4ELMNAALOX5 | |
| SCHEMBL21566079 | 0.77 | APP (0.64) | RAB9AGLAGAA | |
| SCHEMBL17801309 | 0.75 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2KDM4ELMNA | |
| SCHEMBL11778594 | 0.75 | MAPT (0.70) | NPC1RAB9ASMN1; SMN2KDM4ENFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3227283-A1 | BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS | Bayer CropScience AG (DE) | 2017-10-11 | — | — | EP | disclosed |
| WO-2016087371-A1 | BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-06-09 | — | — | WO | disclosed |