Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.49 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.44 |
| ▸ | SULT1A1 | P50225 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.43 |
| ▸ | RELA | Q04206 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CLK1 | P49759 | 1/20 | 0.43 |
| ▸ | CLK2 | P49760 | 1/20 | 0.43 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16568908 | 0.83 | KDM4E (0.64) | APPPIK3CGDYRK1ASULT1A1KDM4E | |
| SCHEMBL17801689 | 0.82 | NPC1 (0.56) | PIK3CGKDM4ENFKB1NFKB2RELA | |
| SCHEMBL17801701 | 0.76 | APP (0.69) | APPSULT1A1KDM4ENFKB1NFKB2 | |
| Hydrochloric Acid SCHEMBL22130203 | 0.75 | APP (0.68) | APPSULT1A1KDM4ENFKB1NFKB2 | |
| SCHEMBL20068806 | 0.73 | DYRK1A (0.63) | APPDYRK1AKDM4ENFKB1NFKB2 | |
| SCHEMBL16568922 | 0.71 | HDAC6 (0.46) | PIK3CGDYRK1AKDM4ENFKB1NFKB2 | |
| SCHEMBL11024521 | 0.71 | KMT2A (0.57) | DYRK1ASMN1; SMN2KMT2ACA2NPC1 | |
| SCHEMBL9620877 | 0.70 | CA2 (0.56) | APPSULT1A1KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL5760456 | 0.70 | MAPT (0.48) | APPDYRK1AKDM4EKMT2ACA2 | |
| SCHEMBL3042970 | 0.69 | APP (0.70) | APPSULT1A1KDM4ENFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3227283-A1 | BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS | Bayer CropScience AG (DE) | 2017-10-11 | — | — | EP | disclosed |
| WO-2016087371-A1 | BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-06-09 | — | — | WO | disclosed |