SCHEMBL17802456

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17802449	0.85	ALDH1A1 (0.43)	RAB9AALDH1A1SMN1; SMN2TP53MAPT
	SCHEMBL17801708	0.85	SMN1; SMN2 (0.47)	RAB9AALDH1A1SMN1; SMN2TP53MAPT
	SCHEMBL17802492	0.79	CYP19A1 (0.52)	RAB9AALDH1A1MAPTCYP1A2CYP3A4
	SCHEMBL12725702	0.77	CYP1A2 (0.69)	RAB9AALDH1A1SMN1; SMN2TP53MAPT
	SCHEMBL14238515	0.76	CYP1A2 (0.52)	RAB9AALDH1A1SMN1; SMN2TP53MAPT
	SCHEMBL14652378	0.76	MEN1 (0.50)	RAB9AALDH1A1SMN1; SMN2TP53MAPT
	SCHEMBL16569011	0.74	ALDH1A1 (0.47)	RAB9AALDH1A1SMN1; SMN2TP53MAPT
	SCHEMBL8255841	0.73	RAB9A (0.68)	RAB9AALDH1A1SMN1; SMN2TP53MAPT
	SCHEMBL30339130	0.73	RAB9A (0.68)	RAB9AALDH1A1SMN1; SMN2TP53MAPT
	SCHEMBL17802503	0.72	RAB9A (0.49)	RAB9AALDH1A1SMN1; SMN2MAPTCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.