Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.35 |
| ▸ | CLK1 | P49759 | 2/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.35 |
| ▸ | CYP2E1 | P05181 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.35 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17802443 | 0.86 | NPC1 (0.39) | NPC1RAB9ACYP3A4CYP2C19CYP1A2 | |
| SCHEMBL17801776 | 0.84 | NPC1 (0.48) | NPC1RAB9ACYP3A4CYP2C19CYP1A2 | |
| SCHEMBL17802490 | 0.78 | NPC1 (0.40) | NPC1RAB9ACYP3A4CYP2C19CYP1A2 | |
| SCHEMBL17802479 | 0.75 | RAB9A (0.45) | NPC1RAB9ACYP3A4CYP2C19CYP1A2 | |
| SCHEMBL17802478 | 0.70 | RAB9A (0.52) | NPC1RAB9ACYP3A4CYP2C19CYP1A2 | |
| SCHEMBL17802472 | 0.70 | NPC1 (0.52) | NPC1RAB9ACYP3A4CYP2C19CYP1A2 | |
| SCHEMBL17813170 | 0.68 | NPC1 (0.40) | NPC1RAB9ACYP2A6MAPTALOX5 | |
| SCHEMBL17802462 | 0.68 | RAB9A (0.47) | NPC1RAB9ACYP2A6ALDH1A1MAPT | |
| SCHEMBL17802492 | 0.68 | CYP19A1 (0.52) | NPC1RAB9ACYP3A4CYP2C19CYP1A2 | |
| SCHEMBL17802503 | 0.67 | RAB9A (0.49) | NPC1RAB9ACYP3A4CYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10138254-B2 | Bicyclic compounds as pest control agents | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-11-27 | — | — | US | disclosed |
| EP-3227302-B1 | BICYCLIC COMPOUNDS AS PEST CONTROLLERS | BAYER CROPSCIENCE AG (DE) | 2018-07-11 | — | — | EP | disclosed |
| US-20170355714-A1 | BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-12-14 | — | — | US | disclosed |
| US-20170355714-A1 | BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-12-14 | — | — | US | disclosed |
| US-20170355714-A1 | BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-12-14 | — | — | US | disclosed |
| EP-3227302-A1 | BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS | Bayer CropScience AG (DE) | 2017-10-11 | — | — | EP | disclosed |
| WO-2016087373-A1 | BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-06-09 | — | — | WO | disclosed |
| WO-2016087373-A1 | BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10138254-B2 | Bicyclic compounds as pest control agents | DDT, BCHE, BAK1 | NPC1 1939/4885RAB9A 736/4885CYP3A4 582/4885 |
| US-20170355714-A1 | BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS | DDT, BCHE, BAK1 | NPC1 1939/4885RAB9A 736/4885CYP3A4 582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.