SCHEMBL17802490

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17802443	0.89	NPC1 (0.39)	NPC1RAB9AALDH1A1KDM4EMAPT
	SCHEMBL17802458	0.78	NPC1 (0.39)	NPC1RAB9AALDH1A1KDM4EMAPT
	SCHEMBL17802479	0.73	RAB9A (0.45)	NPC1RAB9AALDH1A1KDM4EMAPT
	SCHEMBL17802478	0.73	RAB9A (0.52)	NPC1RAB9AALDH1A1KDM4EMAPT
	SCHEMBL17813170	0.71	NPC1 (0.40)	NPC1RAB9AMAPTCYP2A6ALOX5
	SCHEMBL17802472	0.71	NPC1 (0.52)	NPC1RAB9AALDH1A1KDM4EMAPT
	SCHEMBL17802499	0.70	NPC1 (0.49)	NPC1RAB9AKDM4ECYP3A4CYP1A2
	SCHEMBL17802497	0.66	NPC1 (0.47)	NPC1RAB9AALDH1A1KDM4EMAPT
	SCHEMBL17802462	0.66	RAB9A (0.47)	NPC1RAB9AALDH1A1MAPTCYP2A6
	SCHEMBL17802492	0.66	CYP19A1 (0.52)	NPC1RAB9AALDH1A1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.