Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | LOX | P28300 | 1/20 | 0.41 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.39 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.37 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KDM6B | O15054 | 1/20 | 0.36 |
| ▸ | TET3 | O43151 | 1/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | KDM5C | P41229 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30820861 | 0.81 | RECQL (0.44) | RECQLTRPA1LOXLOXL3LOXL2 | |
| SCHEMBL5700002 | 0.81 | RECQL (0.44) | RECQLTRPA1LOXLOXL3LOXL2 | |
| SCHEMBL13742411 | 0.81 | RECQL (0.44) | RECQLTRPA1LOXLOXL3LOXL2 | |
| SCHEMBL40123 | 0.78 | KDM4C (0.61) | RECQLTAS1R3TAS1R1TAS1R2KDM4E | |
| Bromide SCHEMBL7842108 | 0.77 | KDM4C (0.59) | RECQLTAS1R3TAS1R1TAS1R2KDM4E | |
| Hydrochloric Acid SCHEMBL7221156 | 0.77 | KDM4C (0.59) | RECQLTAS1R3TAS1R1TAS1R2KDM4E | |
| SCHEMBL31547893 | 0.77 | KDM4C (0.59) | RECQLTAS1R3TAS1R1TAS1R2KDM4E | |
| Methane SCHEMBL9122275 | 0.77 | KDM5C (0.59) | RECQLTAS1R3TAS1R1TAS1R2KDM4E | |
| SCHEMBL15391333 | 0.76 | RECQL (0.40) | RECQLTRPA1LOXLOXL3LOXL2 | |
| SCHEMBL27623752 | 0.76 | RECQL (0.47) | RECQLLOXLOXL3LOXL2TAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029031-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2016-06-08 | — | — | EP | disclosed |