Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 8/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 3/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17796530 | 0.85 | HPGD (0.56) | HPGDHSP90AA1TSHRCNR2CNR1 | |
| SCHEMBL17796415 | 0.83 | PIK3CA (0.41) | KMT2AALDH1A1L3MBTL3L3MBTL1RAB9A | |
| SCHEMBL17796675 | 0.83 | KMT2A (0.48) | HPGDHSP90AA1KMT2AALDH1A1MEN1 | |
| SCHEMBL17796440 | 0.83 | KMT2A (0.48) | HPGDHSP90AA1KMT2AALDH1A1MEN1 | |
| SCHEMBL17796420 | 0.79 | RAB9A (0.44) | HPGDKMT2AALDH1A1MEN1L3MBTL3 | |
| SCHEMBL17796521 | 0.79 | RAB9A (0.44) | HPGDKMT2AALDH1A1MEN1L3MBTL3 | |
| SCHEMBL24016888 | 0.75 | HPGD (0.55) | HPGDKMT2AALDH1A1MEN1NPSR1 | |
| SCHEMBL15547132 | 0.75 | GABRP (0.44) | ALDH1A1RAB9A | |
| SCHEMBL26140049 | 0.74 | HPGD (0.48) | HPGDKMT2AALDH1A1MEN1NPSR1 | |
| SCHEMBL30414922 | 0.73 | KCNQ3 (0.43) | HPGDALDH1A1POLBL3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029031-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2016-06-08 | — | — | EP | disclosed |