Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TCF4 | P15884 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | FASN | P49327 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22055395 | 0.86 | KDM4E (0.42) | TDP1ALDH1A1RECQLHSD17B10MAPT | |
| SCHEMBL17804320 | 0.80 | CYP3A4 (0.47) | TDP1TSHRALDH1A1RECQLHPGD | |
| SCHEMBL13468056 | 0.77 | KDM4E (0.46) | TDP1ALDH1A1HSD17B10MAPTKDM4E | |
| SCHEMBL600598 | 0.77 | KDM4E (0.66) | TDP1ALDH1A1RECQLHSD17B10MAPT | |
| SCHEMBL21543950 | 0.77 | ALDH1A1 (0.51) | TSHRALDH1A1RECQLHPGDALOX15 | |
| SCHEMBL17804340 | 0.76 | TSHR (0.40) | TDP1TSHRALDH1A1RECQLHPGD | |
| SCHEMBL17804328 | 0.75 | CYP1A2 (0.41) | TDP1TSHRALDH1A1RECQLHPGD | |
| SCHEMBL12499964 | 0.72 | KDM4E (0.47) | TDP1TSHRALDH1A1HPGDALOX15 | |
| SCHEMBL7476851 | 0.72 | HSD17B10 (0.46) | TDP1TSHRALDH1A1RECQLHPGD | |
| SCHEMBL29920315 | 0.72 | KDM4E (0.47) | TDP1TSHRALDH1A1HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2697198-B1 | SUBSTITUTED BENZENE COMPOUNDS | EPIZYME INC (US) | 2016-06-08 | — | — | EP | disclosed |