Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TCF4 | P15884 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | FASN | P49327 | 2/20 | 0.33 |
| ▸ | HMGCR | P04035 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17804333 | 0.76 | TDP1 (0.43) | TSHRTDP1ALDH1A1HPGDALOX15 | |
| SCHEMBL17804320 | 0.76 | CYP3A4 (0.47) | TSHRTDP1ALDH1A1HPGDALOX15 | |
| SCHEMBL17804326 | 0.75 | KDM4E (0.47) | TSHRTDP1ALDH1A1HPGDALOX15 | |
| SCHEMBL7476851 | 0.69 | HSD17B10 (0.46) | TSHRTDP1ALDH1A1HPGDALOX15 | |
| SCHEMBL11271074 | 0.68 | HPGD (0.48) | TSHRTDP1ALDH1A1HPGDALOX15 | |
| SCHEMBL11071972 | 0.67 | TSHR (0.43) | TSHRTDP1ALDH1A1HPGDALOX15 | |
| Hydrochloric Acid SCHEMBL11264387 | 0.67 | HPGD (0.47) | TSHRTDP1ALDH1A1HPGDALOX15 | |
| SCHEMBL9559780 | 0.66 | MAPT (0.49) | TSHRTDP1ALDH1A1HPGDALOX15 | |
| SCHEMBL26596703 | 0.65 | KDM4E (0.44) | TDP1HPGDHSD17B10KDM4EMEN1 | |
| SCHEMBL4904631 | 0.65 | HSD17B3 (0.60) | TDP1ALDH1A1HPGDHSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2697198-B1 | SUBSTITUTED BENZENE COMPOUNDS | EPIZYME INC (US) | 2016-06-08 | — | — | EP | disclosed |