Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.56 |
| ▸ | ESR1 | P03372 | 2/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.56 |
| ▸ | TACR2 | P21452 | 2/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | SHBG | P04278 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.56 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22578200 | 1.00 | KAT8 (0.59) | KAT8PTGS2ESR1ADRA2AADORA3 | |
| SCHEMBL18676879 | 1.00 | KAT8 (0.59) | KAT8PTGS2ESR1ADRA2AADORA3 | |
| SCHEMBL20047782 | 0.98 | KAT8 (0.57) | KAT8PTGS2ESR1ADRA2AADORA3 | |
| SCHEMBL11155646 | 0.93 | NPC1 (0.55) | KAT8PTGS2ESR1ADRA2AADORA3 | |
| SCHEMBL27693940 | 0.86 | PPARA (0.59) | KAT8PTGS2ESR1ADRA2AADORA3 | |
| SCHEMBL566565 | 0.85 | CNR1 (0.64) | ESR1CYP3A4KDM4EHIF1AHSD17B10 | |
| SCHEMBL11721061 | 0.83 | IGF1R (0.76) | KAT8PTGS2ESR1ADRA2AADORA3 | |
| SCHEMBL11616856 | 0.83 | IGF1R (0.76) | KAT8PTGS2ESR1ADRA2AADORA3 | |
| SCHEMBL70343 | 0.83 | IGF1R (0.76) | KAT8PTGS2ESR1ADRA2AADORA3 | |
| SCHEMBL68207 | 0.83 | IGF1R (0.76) | KAT8PTGS2ESR1ADRA2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111491942-B | Metal-ligand complex, catalyst composition, and method for producing same | 沙特基础工业爱思开NEXLENE私人有限公司 | 2024-01-12 | — | — | CN | disclosed |
| US-11505563-B2 | Metal-ligand complex, catalyst composition for ethylene-based polymerization including the same, and method for preparing ethylene-based polymer using the same | SABIC SK NEXLENE COMPANY PTE. LTD. (SG) | 2022-11-22 | — | — | US | disclosed |
| EP-3730501-B1 | METAL-LIGAND COMPLEX, CATALYST COMPOSITION COMPRISING SAME FOR ETHYLENE-BASED POLYMERIZATION, AND METHOD FOR PREPARING ETHYLENE-BASED POLYMER BY USING SAME | SABIC SK NEXLENE COMPANY PTE LTD (SG) | 2022-09-14 | — | — | EP | disclosed |
| US-20220135599-A1 | METAL-LIGAND COMPLEX, CATALYST COMPOSITION COMPRISING SAME FOR ETHYLENE BASED POLYMERIZATION, AND METHOD FOR PREPARING ETHYLENE-BASED POLYMER BY USING SAME | SABIC SK NEXLENE COMPANY PTE. LTD. (SG) | 2022-05-05 | — | — | US | disclosed |
| EP-3730501-A1 | METAL-LIGAND COMPLEX, CATALYST COMPOSITION COMPRISING SAME FOR ETHYLENE-BASED POLYMERIZATION, AND METHOD FOR PREPARING ETHYLENE-BASED POLYMER BY USING SAME | Sabic Sk Nexlene Company Pte. Ltd. (SG) | 2020-10-28 | — | — | EP | disclosed |
| CN-111491942-A | Metal-ligand complex, catalyst composition for ethylene polymerization comprising same, and method for producing ethylene polymer using same | 沙特基础工业爱思开NEXLENE私人有限公司 | 2020-08-04 | — | — | CN | disclosed |
| US-9707205-B2 | S1P receptors modulators and their use thereof | AKAAL PHARMA PTY LTD. (AU) | 2017-07-18 | — | — | US | disclosed |
| EP-2344484-B1 | S1P RECEPTORS MODULATORS AND USE THEREOF | AKAAL PHARMA PTY LTD (AU) | 2016-06-08 | — | — | EP | disclosed |
| US-20160038455-A1 | S1P RECEPTORS MODULATORS AND THEIR USE THEREOF | AKAAL PHARMA PTY LTD. (AU) | 2016-02-11 | — | — | US | disclosed |
| US-9193716-B2 | S1P receptors modulators and their use thereof | AKAAL PHARMA PTY LTD. (AU) | 2015-11-24 | — | — | US | disclosed |
| WO-2014063199-A1 | ORGANIC COMPOUNDS | AKAAL PHARMA PTY LTD (AU) | 2014-05-01 | — | — | WO | disclosed |
| US-20140066427-A1 | S1P Receptors Modulators and Their Use Thereof | AKAAL PHARMA PTY LTD. (AU) | 2014-03-06 | — | — | US | disclosed |
| US-8592399-B2 | S1P receptors modulators and their use thereof | AKAAL PHARMA PTY LTD. (AU) | 2013-11-26 | — | — | US | disclosed |
| US-20110318388-A1 | S1P Receptors Modulators and Their Use Thereof | AKAAL PHARMA PTY LTD (AU) | 2011-12-29 | — | — | US | disclosed |
| CN-102186845-A | S1p receptors modulators and their use thereof | AKAAL PHARMA PTY LTD | 2011-09-14 | — | — | CN | disclosed |
| EP-2344484-A1 | S1P RECEPTORS MODULATORS AND THEIR USE THEREOF | Akaal Pharma Pty Ltd (AU) | 2011-07-20 | — | — | EP | disclosed |
| WO-2010043000-A1 | S1P RECEPTORS MODULATORS AND THEIR USE THEREOF | AKAAL PHARMA PTY LTD (AU) | 2010-04-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160038455-A1 | S1P RECEPTORS MODULATORS AND THEIR USE THEREOF | S1PR1, S1PR5, S1PR2 | KAT8 3964/4885PTGS2 1012/4885ESR1 1797/4885 |
| US-11505563-B2 | Metal-ligand complex, catalyst composition for ethylene-based polymerization including the same, and method for preparing ethylene-based polymer using the same | EPRS1, NOTUM, ELL | KAT8 2160/4885PTGS2 707/4885ESR1 23/4885 |
| US-20110318388-A1 | S1P Receptors Modulators and Their Use Thereof | S1PR1, S1PR5, S1PR2 | KAT8 3964/4885PTGS2 1012/4885ESR1 1797/4885 |
| US-20140066427-A1 | S1P Receptors Modulators and Their Use Thereof | S1PR1, S1PR2, S1PR5 | KAT8 3602/4885PTGS2 1213/4885ESR1 2088/4885 |
| US-20220135599-A1 | METAL-LIGAND COMPLEX, CATALYST COMPOSITION COMPRISING SAME FOR ETHYLENE BASED POLYMERIZATION, AND METHOD FOR PREPARING ETHYLENE-BASED POLYMER BY USING SAME | NOTUM, EPRS1, ESD | KAT8 1922/4885PTGS2 664/4885ESR1 51/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.