SCHEMBL17805296

SCHEMBL17805296

CC(F)CN(Cc1cnc(Cl)c(Cl)c1)C1=CC(=S)OC1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12863911 0.91
SCHEMBL1165537 0.83
SCHEMBL1165111 0.81
SCHEMBL1165038 0.80 ALDH1A1 (0.30) ALDH1A1NPSR1
SCHEMBL13026050 0.78 ALDH1A1 (0.30) ALDH1A1NPSR1
SCHEMBL1164988 0.76 ALDH1A1 (0.30) ALDH1A1
SCHEMBL1165000 0.74 CHRNA1 (0.31)
SCHEMBL1165256 0.72
SCHEMBL1165504 0.71
SCHEMBL1165106 0.70 DRD2 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2262798-B1 SUBSTITUTED ENAMINOTHIOCARBONYL COMPOUNDS BAYER IP GMBH (DE) 2016-06-08 EP disclosed