Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16442865 | 0.93 | MRGPRX4 (0.40) | MRGPRX4SLC22A12NR1H4CYP3A4CYP2C9 | |
| SCHEMBL16442780 | 0.93 | MRGPRX4 (0.47) | MRGPRX4SLC22A12NR1H4CYP3A4CYP2C9 | |
| SCHEMBL17806065 | 0.92 | MRGPRX4 (0.40) | MRGPRX4SLC22A12NR1H4GRIN1GRIN2B | |
| SCHEMBL17806066 | 0.92 | MRGPRX4 (0.36) | MRGPRX4SLC22A12NR1H4CYP3A4CYP2C9 | |
| SCHEMBL17788128 | 0.91 | MRGPRX4 (0.39) | MRGPRX4SLC22A12NR1H4GRIN1GRIN2B | |
| SCHEMBL17806061 | 0.91 | MRGPRX4 (0.39) | MRGPRX4NR1H4CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL17806079 | 0.91 | MRGPRX4 (0.39) | MRGPRX4NR1H4GRIN1GRIN2BCYP3A4 | |
| SCHEMBL16442793 | 0.91 | MRGPRX4 (0.37) | MRGPRX4NR1H4GRIN1GRIN2BADORA1 | |
| SCHEMBL17806101 | 0.91 | MRGPRX4 (0.35) | MRGPRX4SLC22A12NR1H4CYP3A4CYP2C9 | |
| SCHEMBL17806069 | 0.90 | MRGPRX4 (0.39) | MRGPRX4GRIN1GRIN2BPTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9512090-B2 | Tetrazolinone compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-12-06 | — | — | US | disclosed |
| US-20160159755-A1 | TETRAZOLINONE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160159755-A1 | TETRAZOLINONE COMPOUND AND USE THEREOF | CYP1A1, CASP1, TCOF1 | MRGPRX4 1910/4885SLC22A12 3833/4885NR1H4 1489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.