SCHEMBL1780685

SCHEMBL1780685

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nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MGAM O43451 8/20 0.39
SI P14410 1/20 0.38
LMNA P02545 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1781149 1.00 MGAM (0.39) MGAMSILMNAL3MBTL1TDP1
SCHEMBL1781151 1.00 MGAM (0.39) MGAMSILMNAL3MBTL1TDP1
SCHEMBL207381 0.82 CA1 (0.31)
SCHEMBL2993224 0.81 TYR (0.34)
SCHEMBL24409872 0.80 TYR (0.38)
SCHEMBL259958 0.75 LMNA (0.44) MGAMSILMNAL3MBTL1TDP1
SCHEMBL29393460 0.75 MGAM (0.35) MGAM
SCHEMBL11086284 0.74 TYR (0.39) MGAMLMNA
Isomalt SCHEMBL21140451 0.73 GAA (0.47) L3MBTL1
Isomalt SCHEMBL348201 0.73 GAA (0.47) L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8987216-B2 Polysulfated glycosides and salts thereof Teva Hungary Pharmaceutical Marketing Private Limited Company (HU) 2015-03-24 US disclosed
US-8987216-B2 Polysulfated glycosides and salts thereof Teva Hungary Pharmaceutical Marketing Private Limited Company (HU) 2015-03-24 US disclosed
US-8987216-B2 Polysulfated glycosides and salts thereof Teva Hungary Pharmaceutical Marketing Private Limited Company (HU) 2015-03-24 US disclosed
US-20110118198-A1 POLYSULFATED GLYCOSIDES AND SALTS THEREOF IVAX DRUG RESEARCH INSTITUTE LTD. (HU) 2011-05-19 US disclosed
US-20110118198-A1 POLYSULFATED GLYCOSIDES AND SALTS THEREOF IVAX DRUG RESEARCH INSTITUTE LTD. (HU) 2011-05-19 US disclosed
US-20110118198-A1 POLYSULFATED GLYCOSIDES AND SALTS THEREOF IVAX DRUG RESEARCH INSTITUTE LTD. (HU) 2011-05-19 US disclosed
US-7902158-B2 Polysulfated glycosides and salts thereof Ivax Drug Research Ltd. (HU) 2011-03-08 US disclosed
US-7902158-B2 Polysulfated glycosides and salts thereof Ivax Drug Research Ltd. (HU) 2011-03-08 US disclosed
US-7902158-B2 Polysulfated glycosides and salts thereof Ivax Drug Research Ltd. (HU) 2011-03-08 US disclosed
EP-1778709-B1 POLYSULFATED GLYCOSIDES AND SALTS THEREOF IVAX DRUG RES INST LTD (HU) 2008-05-28 EP disclosed
US-20070281893-A1 Polysulfated Glycosides And Salts Thereof IVAX DRUG RESEARCH INSTITUTE LTD (HU) 2007-12-06 US disclosed
US-20070281893-A1 Polysulfated Glycosides And Salts Thereof IVAX DRUG RESEARCH INSTITUTE LTD (HU) 2007-12-06 US disclosed
US-20070281893-A1 Polysulfated Glycosides And Salts Thereof IVAX DRUG RESEARCH INSTITUTE LTD (HU) 2007-12-06 US disclosed
CN-101014607-A Polysulfated glycosides and salts thereof IVAX DRUG RES INST LTD (HU) 2007-08-08 CN disclosed
EP-1778709-A2 POLYSULFATED GLYCOSIDES AND SALTS THEREOF IVAX Drug Research Institute Ltd (HU) 2007-05-02 EP disclosed
WO-2006017726-A2 POLYSULFATED GLYCOSIDES AND SALTS THEREOF IVAX DRUG RESEARCH INSTITUTE LTD (HU) 2006-02-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110118198-A1 POLYSULFATED GLYCOSIDES AND SALTS THEREOF CFTR, AREG, STS MGAM 616/4885SI 263/4885LMNA 4475/4885
US-20070281893-A1 Polysulfated Glycosides And Salts Thereof CFTR, AREG, STS MGAM 616/4885SI 263/4885LMNA 4475/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.