Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.33 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | REN | P00797 | 3/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4364632 | 0.84 | ALDH1A1 (0.45) | KMT2ANPC1MEN1ZDHHC20ZDHHC2 | |
| SCHEMBL9186900 | 0.75 | ALDH1A1 (0.39) | KMT2ANPC1MEN1ZDHHC20ZDHHC2 | |
| SCHEMBL14514537 | 0.74 | EPHX1 (0.52) | KMT2ANPC1ALDH1A1TSHRMAPK1 | |
| SCHEMBL15429220 | 0.73 | ZDHHC20 (0.33) | KMT2AZDHHC20ZDHHC2ALDH1A1TSHR | |
| SCHEMBL220086 | 0.72 | EPHX1 (0.55) | KMT2ANPC1ALDH1A1TSHRMAPK1 | |
| SCHEMBL15178228 | 0.71 | EPHX2 (0.31) | — | |
| SCHEMBL17915685 | 0.70 | TSHR (0.41) | KMT2AZDHHC20ZDHHC2ALDH1A1TSHR | |
| SCHEMBL15429223 | 0.70 | ALDH1A1 (0.34) | KMT2AZDHHC20ZDHHC2ALDH1A1TSHR | |
| SCHEMBL10729681 | 0.70 | ALDH1A1 (0.52) | KMT2ANPC1MEN1ZDHHC20ZDHHC2 | |
| SCHEMBL368411 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160157764-A1 | MICRONEEDLE ARRAY DEVICE AND METHOD OF MAKING | STMICROELECTRONICS S.R.L. (IT) | 2016-06-09 | — | — | US | disclosed |