SCHEMBL1780807

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1001096	0.86	ADORA2B (0.67)	ADORA2BADORA2AADORA1KDM4EMEN1
	SCHEMBL1948455	0.85	ADORA2B (1.00)	ADORA2BADORA2AADORA1KDM4EMEN1
	SCHEMBL946126	0.85	ADORA2B (0.72)	ADORA2BADORA2AADORA1KDM4EMEN1
	SCHEMBL1497235	0.84	ADORA2B (0.65)	ADORA2BADORA2AADORA1KDM4EMEN1
	SCHEMBL1497285	0.84	ADORA2B (0.65)	ADORA2BADORA2AADORA1KDM4EMEN1
	SCHEMBL4510610	0.83	ADORA2B (0.67)	ADORA2BADORA2AADORA1KDM4EMEN1
	SCHEMBL1497219	0.83	ADORA2B (0.64)	ADORA2BADORA2AADORA1KDM4EMEN1
	SCHEMBL1497249	0.82	ADORA2B (0.62)	ADORA2BADORA2AADORA1KDM4EMEN1
	SCHEMBL1497221	0.82	ADORA2B (0.62)	ADORA2BADORA2AADORA1KDM4EMEN1
	SCHEMBL14564546	0.82	ADORA2B (0.79)	ADORA2BADORA2AADORA1KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.