SCHEMBL17809113

SCHEMBL17809113

c1ccc(-c2ccc(-c3nc(-c4ccccc4)nc(-c4cccc(-n5c6ccccc6c6ccc7c8ccccc8n(-c8ccc(-c9cccc(-c%10ccccc%10)c9)cc8)c7c65)c4)n3)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.41
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
KMT2A Q03164 2/20 0.36
MEN1 O00255 1/20 0.36
GAA P10253 1/20 0.36
PDE10A Q9Y233 1/20 0.35
AVPR1A P37288 1/20 0.35
NR3C1 P04150 1/20 0.34
IL1R1 P14778 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24078671 1.00 KDM4E (0.41) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL17809101 1.00 KDM4E (0.41) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL26472757 0.99 KDM4E (0.42) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL25965921 0.99 KDM4E (0.42) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL24078632 0.97 L3MBTL1 (0.44) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL22596033 0.97 L3MBTL1 (0.44) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL17809127 0.97 L3MBTL1 (0.44) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL25009440 0.97 KDM4E (0.40) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL21365578 0.97 L3MBTL1 (0.44) KDM4EATML3MBTL1KMT2AMEN1
SCHEMBL21365573 0.97 L3MBTL1 (0.44) KDM4EATML3MBTL1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160163995-A1 ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2016-06-09 US disclosed
US-20160163995-A1 ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2016-06-09 US disclosed