SCHEMBL21365573

SCHEMBL21365573

c1ccc(-c2cccc(-c3nc(-c4ccccc4)nc(-c4ccc(-n5c6ccccc6c6ccc7c8ccccc8n(-c8ccccc8)c7c65)cc4)n3)c2)cc1

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.44
KDM4E B2RXH2 1/20 0.44
ATM Q13315 1/20 0.44
AVPR1A P37288 1/20 0.36
NR3C1 P04150 1/20 0.36
KMT2A Q03164 3/20 0.35
IL1R1 P14778 1/20 0.35
HDAC4 P56524 1/20 0.35
MEN1 O00255 2/20 0.35
ALDH1A1 P00352 2/20 0.35
MAPT P10636 2/20 0.35
HPGD P15428 1/20 0.35
HTT P42858 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21365578 1.00 L3MBTL1 (0.44) L3MBTL1KDM4EATMAVPR1ANR3C1
SCHEMBL22596033 1.00 L3MBTL1 (0.44) L3MBTL1KDM4EATMAVPR1ANR3C1
SCHEMBL24078671 0.97 KDM4E (0.41) L3MBTL1KDM4EATMAVPR1ANR3C1
SCHEMBL17809101 0.97 KDM4E (0.41) L3MBTL1KDM4EATMAVPR1ANR3C1
SCHEMBL17809113 0.97 KDM4E (0.41) L3MBTL1KDM4EATMAVPR1ANR3C1
SCHEMBL19474357 0.97 KDM4E (0.42) L3MBTL1KDM4EATMAVPR1ANR3C1
SCHEMBL17809103 0.97 KDM4E (0.42) L3MBTL1KDM4EATMAVPR1ANR3C1
SCHEMBL19474397 0.97 KDM4E (0.42) L3MBTL1KDM4EATMAVPR1ANR3C1
SCHEMBL25965921 0.96 KDM4E (0.42) L3MBTL1KDM4EATMAVPR1AKMT2A
SCHEMBL26472757 0.96 KDM4E (0.42) L3MBTL1KDM4EATMAVPR1ANR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3767698-B1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MAT CO LTD (JP) 2023-10-25 EP disclosed
US-20230255106-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2023-08-10 US disclosed
US-20230255106-A1 ORGANIC ELECTROLUMINESCENT APPARATUS MERCK PATENT GMBH (DE) 2023-08-10 US disclosed
US-20230172065-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-06-01 US disclosed
US-20230172065-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-06-01 US disclosed
US-11374178-B2 Organic electroluminescent element NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2022-06-28 US disclosed
WO-2022015084-A1 ORGANIC LIGHT-EMITTING ELEMENT 주식회사 엘지화학 2022-01-20 WO disclosed
US-20210119144-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2021-04-22 US disclosed
EP-3767698-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL Chemical & Material Co., Ltd. (JP) 2021-01-20 EP disclosed
EP-3605634-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL Chemical & Material Co., Ltd. (JP) 2020-02-05 EP disclosed
WO-2019176605-A1 ORGANIC ELECTROLUMINESCENT ELEMENT 日鉄ケミカル&マテリアル株式会社 2019-09-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230172065-A1 ORGANIC LIGHT EMITTING DEVICE CRY1, CYP1A2, CYP1A1 L3MBTL1 1309/4885KDM4E 2372/4885ATM 2759/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.