SCHEMBL17809142

SCHEMBL17809142

c1ccc(-c2cc(-c3ccccc3)nc(-c3cccc(-n4c5ccccc5c5ccc6c7ccccc7n(-c7cccc8c7oc7ccccc78)c6c54)c3)n2)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.34
ALDH1A1 P00352 9/20 0.34
MEN1 O00255 8/20 0.34
KMT2A Q03164 8/20 0.34
KDM4E B2RXH2 6/20 0.34
LMNA P02545 6/20 0.34
HPGD P15428 4/20 0.34
TSHR P16473 4/20 0.33
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
GAA P10253 2/20 0.31
ALOX5 P09917 1/20 0.31
MAPK1 P28482 3/20 0.31
HSD17B10 Q99714 2/20 0.31
POLB P06746 2/20 0.31
NTSR1 P30989 1/20 0.31
GLA P06280 1/20 0.30
NPSR1 Q6W5P4 3/20 0.30
PPARG P37231 1/20 0.30
RXFP1 Q9HBX9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19129561 0.94 MAPT (0.36) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL17809143 0.94 MAPT (0.36) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL22192497 0.93 KDM4E (0.34) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL17809148 0.92 MAPT (0.35) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL17809140 0.92 KDM4E (0.32) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL17809129 0.92 MAPT (0.36) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL21669020 0.92 KDM4E (0.35) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL17809135 0.92 MAPT (0.36) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL17809137 0.91 MAPT (0.35) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL24216500 0.91 PTPRF (0.35) MAPTALDH1A1MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160163995-A1 ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2016-06-09 US disclosed
US-20160163995-A1 ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2016-06-09 US disclosed