SCHEMBL17809140

SCHEMBL17809140

c1ccc(-c2cc(-c3cccc(-n4c5ccccc5c5ccc6c7ccccc7n(-c7cccc8c7oc7ccccc78)c6c54)c3)cc(-c3ccccc3)n2)cc1

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
MEN1 O00255 4/20 0.31
KMT2A Q03164 4/20 0.31
GAA P10253 2/20 0.31
ALOX5 P09917 1/20 0.31
ALDH1A1 P00352 3/20 0.31
POLB P06746 2/20 0.31
TSHR P16473 2/20 0.31
BRCA1 P38398 1/20 0.31
HSD17B10 Q99714 1/20 0.31
GABRG2 P18507 1/20 0.31
GABRB3 P28472 1/20 0.31
GABRA5 P31644 1/20 0.31
GABRA3 P34903 1/20 0.31
LMNA P02545 2/20 0.30
PPARG P37231 1/20 0.30
RXFP1 Q9HBX9 1/20 0.30
NR2E3 Q9Y5X4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17809132 0.96 ALOX5 (0.32) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL17809131 0.92 ALOX5 (0.33) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL17809142 0.92 MAPT (0.34) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL17809136 0.91 ALOX5 (0.33) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL23203963 0.90 KDM4E (0.37) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL26413259 0.89 KDM4E (0.36) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL17809143 0.87 MAPT (0.36) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL17809385 0.87 KDM4E (0.33) KDM4EATML3MBTL1
SCHEMBL17809307 0.86 KDM4E (0.32) KDM4EATML3MBTL1ALOX5
SCHEMBL12690801 0.85 L3MBTL1 (0.45) KDM4EATML3MBTL1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160163995-A1 ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2016-06-09 US disclosed
US-20160163995-A1 ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2016-06-09 US disclosed