SCHEMBL17809145

SCHEMBL17809145

c1ccc(-c2ccc(-c3cc(-c4ccccc4)nc(-n4c5ccccc5c5ccc6c7ccccc7n(-c7cccc8c7oc7ccccc78)c6c54)c3)cc2)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 3/20 0.34
ALOX5 P09917 1/20 0.33
PTGER1 P34995 1/20 0.31
MEN1 O00255 3/20 0.30
KMT2A Q03164 3/20 0.30
PIK3CD O00329 1/20 0.30
PIK3CB P42338 1/20 0.30
MAPT P10636 3/20 0.30
ALDH1A1 P00352 2/20 0.30
MAPK1 P28482 2/20 0.30
TDP1 Q9NUW8 2/20 0.30
PTPRF P10586 2/20 0.30
PTPN2 P17706 2/20 0.30
PTPN1 P18031 2/20 0.30
KDM4E B2RXH2 1/20 0.30
HPGD P15428 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
NPC1 O15118 1/20 0.30
LMNA P02545 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17246051 0.91 PTGER1 (0.32) PRKDCALOX5PTGER1MEN1KMT2A
SCHEMBL17809149 0.91 MAPT (0.40) PRKDCALOX5MEN1KMT2APIK3CB
SCHEMBL17809147 0.91 MAPT (0.40) PRKDCALOX5MEN1KMT2APIK3CB
SCHEMBL17809131 0.90 ALOX5 (0.33) PRKDCALOX5MEN1KMT2AMAPT
SCHEMBL17809138 0.88 MAPT (0.41) PRKDCMEN1KMT2APIK3CBMAPT
SCHEMBL17809132 0.88 ALOX5 (0.32) PRKDCALOX5MEN1KMT2AMAPT
SCHEMBL17809144 0.87 ALOX5 (0.34) PRKDCALOX5MEN1KMT2AMAPT
SCHEMBL17809140 0.85 KDM4E (0.32) PRKDCALOX5MEN1KMT2AMAPT
SCHEMBL17809136 0.85 ALOX5 (0.33) PRKDCALOX5PTGER1MEN1KMT2A
SCHEMBL17809141 0.85 ALOX5 (0.33) PRKDCALOX5PTGER1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160163995-A1 ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2016-06-09 US disclosed
US-20160163995-A1 ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2016-06-09 US disclosed