SCHEMBL17809158

SCHEMBL17809158

c1ccc(-c2cc(-c3ccccc3)cc(-n3c4ccccc4c4ccc5c6ccccc6n(-c6cccc(-c7cc(-c8ccccc8)nc(-c8ccccc8)c7)c6)c5c43)c2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.39
KDM4E B2RXH2 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
GAA P10253 1/20 0.36
CYP19A1 P11511 1/20 0.36
GABRG2 P18507 1/20 0.36
GABRB3 P28472 1/20 0.36
GABRA5 P31644 1/20 0.36
GABRA3 P34903 1/20 0.36
PDE10A Q9Y233 1/20 0.35
OPRD1 P41143 1/20 0.34
RAB9A P51151 1/20 0.34
TET2 Q6N021 1/20 0.34
TET1 Q8NFU7 1/20 0.34
ALDH1A1 P00352 2/20 0.33
ACHE P22303 1/20 0.33
FAAH O00519 1/20 0.33
HSP90AA1 P07900 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12693846 1.00 ATM (0.39) ATMKDM4EL3MBTL1MEN1KMT2A
SCHEMBL17809174 0.97 ATM (0.41) ATMKDM4EL3MBTL1MEN1KMT2A
SCHEMBL17809155 0.96 KDM4E (0.38) ATMKDM4EL3MBTL1MEN1KMT2A
SCHEMBL22595403 0.96 ATM (0.40) ATMKDM4EL3MBTL1MEN1KMT2A
SCHEMBL17809109 0.95 KDM4E (0.41) ATMKDM4EL3MBTL1MEN1KMT2A
SCHEMBL17809170 0.95 KDM4E (0.39) ATMKDM4EL3MBTL1MEN1KMT2A
SCHEMBL22596267 0.95 L3MBTL1 (0.42) ATMKDM4EL3MBTL1MEN1KMT2A
SCHEMBL12690801 0.95 L3MBTL1 (0.45) ATMKDM4EL3MBTL1MEN1KMT2A
SCHEMBL16674328 0.95 ATM (0.41) ATMKDM4EL3MBTL1MEN1KMT2A
SCHEMBL12691122 0.95 L3MBTL1 (0.40) ATMKDM4EL3MBTL1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160163995-A1 ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2016-06-09 US disclosed
US-20160163995-A1 ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2016-06-09 US disclosed