SCHEMBL12691122

SCHEMBL12691122

c1ccc(-c2cc(-c3ccccc3)cc(-n3c4ccccc4c4ccc5c6ccccc6n(-c6cc(-c7ccccc7)cc(-c7cc(-c8ccccc8)nc(-c8ccccc8)c7)c6)c5c43)c2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.40
KDM4E B2RXH2 4/20 0.40
CYP19A1 P11511 1/20 0.40
ATM Q13315 1/20 0.40
ACHE P22303 1/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
DHODH Q02127 1/20 0.35
ADORA1 P30542 2/20 0.35
ADORA3 P0DMS8 1/20 0.35
ADORA2B P29275 1/20 0.35
RAB9A P51151 1/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
HPGD P15428 3/20 0.34
ALDH1A1 P00352 2/20 0.34
ADORA2A P29274 1/20 0.34
LMNA P02545 2/20 0.34
PDE10A Q9Y233 1/20 0.34
MCL1 Q07820 1/20 0.34
MYC P01106 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12131948 0.97 L3MBTL1 (0.40) L3MBTL1KDM4ECYP19A1ATMACHE
SCHEMBL17809152 0.96 KDM4E (0.40) L3MBTL1KDM4ECYP19A1ATMACHE
SCHEMBL17809158 0.95 ATM (0.39) L3MBTL1KDM4ECYP19A1ATMACHE
SCHEMBL12693846 0.95 ATM (0.39) L3MBTL1KDM4ECYP19A1ATMACHE
SCHEMBL17809155 0.94 KDM4E (0.38) L3MBTL1KDM4ECYP19A1ATMACHE
SCHEMBL17809174 0.92 ATM (0.41) L3MBTL1KDM4ECYP19A1ATMACHE
SCHEMBL17809116 0.91 KDM4E (0.43) L3MBTL1KDM4ECYP19A1ATMACHE
SCHEMBL17809184 0.91 KDM4E (0.43) L3MBTL1KDM4ECYP19A1ATMACHE
SCHEMBL12131949 0.91 L3MBTL1 (0.44) L3MBTL1KDM4EATMACHEMEN1
SCHEMBL17809165 0.91 MEN1 (0.35) L3MBTL1KDM4ECYP19A1ATMACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4039774-B1 ORGANIC LIGHT-EMITTING MATERIAL AND ORGANIC LIGHT-EMITTING ELEMENT NIPPON STEEL CHEMICAL & MAT CO LTD (JP) 2023-09-20 EP disclosed
EP-3176241-A1 ORGANIC LIGHT-EMITTING MATERIAL AND ORGANIC LIGHT-EMITTING ELEMENT Nippon Steel & Sumikin Chemical Co., Ltd. (JP) 2017-06-07 EP disclosed
EP-2535957-B1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL & SUMIKIN CHEM CO (JP) 2017-01-04 EP disclosed
US-9156843-B2 Organic electroluminescent device comprising an organic layer containing an indolocarbazole compound NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2015-10-13 US disclosed
US-9156843-B2 Organic electroluminescent device comprising an organic layer containing an indolocarbazole compound NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2015-10-13 US disclosed
US-20150166886-A1 FLUORESCENCE AND DELAYED FLUORESCENCE-TYPE ORGANIC LIGHT-EMITTING MATERIAL AND ELEMENT KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2015-06-18 US disclosed
US-20150166886-A1 FLUORESCENCE AND DELAYED FLUORESCENCE-TYPE ORGANIC LIGHT-EMITTING MATERIAL AND ELEMENT KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2015-06-18 US disclosed
US-8993129-B2 Fluorescence and delayed fluorescence-type organic light-emitting material and element NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2015-03-31 US disclosed
US-20120305903-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2012-12-06 US disclosed
US-20120305903-A1 ORGANIC ELECTROLUMINESCENT DEVICE NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2012-12-06 US disclosed
US-20120241732-A1 ORGANIC LIGHT-EMITTING MATERIAL AND ORGANIC LIGHT-EMITTING ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2012-09-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150166886-A1 FLUORESCENCE AND DELAYED FLUORESCENCE-TYPE ORGANIC LIGHT-EMITTING MATERIAL AND ELEMENT LEF1, EML4, TEAD1 L3MBTL1 155/4885KDM4E 2765/4885CYP19A1 1396/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.