SCHEMBL17809192

SCHEMBL17809192

c1ccc(-c2ccc(-n3c4ccccc4c4ccc5c6ccccc6n(-c6cc(-c7ccccc7)nc(-c7ccccc7)c6)c5c43)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.43
L3MBTL1 Q9Y468 3/20 0.43
ATM Q13315 1/20 0.43
DHODH Q02127 1/20 0.38
MAPT P10636 3/20 0.38
ALDH1A1 P00352 3/20 0.38
HPGD P15428 2/20 0.38
MAPK1 P28482 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
HDAC4 P56524 1/20 0.37
ACHE P22303 1/20 0.36
CTRC Q99895 1/20 0.35
KMT2A Q03164 4/20 0.35
MEN1 O00255 3/20 0.35
HSP90AA1 P07900 1/20 0.35
NR3C1 P04150 1/20 0.35
AHR P35869 1/20 0.35
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
IL1R1 P14778 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17809122 1.00 KDM4E (0.43) KDM4EL3MBTL1ATMDHODHMAPT
SCHEMBL16674331 0.97 L3MBTL1 (0.47) KDM4EL3MBTL1ATMDHODHMAPT
SCHEMBL17809107 0.96 KDM4E (0.40) KDM4EL3MBTL1ATMDHODHMAPT
SCHEMBL12131929 0.96 KDM4E (0.50) KDM4EL3MBTL1ATMDHODHMAPT
SCHEMBL12131922 0.96 L3MBTL1 (0.49) KDM4EL3MBTL1ATMMAPTALDH1A1
SCHEMBL10206020 0.96 KDM4E (0.49) KDM4EL3MBTL1ATMDHODHMAPT
SCHEMBL17809184 0.94 KDM4E (0.43) KDM4EL3MBTL1ATMDHODHMAPT
SCHEMBL17809116 0.94 KDM4E (0.43) KDM4EL3MBTL1ATMDHODHMAPT
SCHEMBL10069437 0.94 L3MBTL1 (0.50) KDM4EL3MBTL1ATMMAPTALDH1A1
SCHEMBL12131949 0.94 L3MBTL1 (0.44) KDM4EL3MBTL1ATMDHODHMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230136708-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-05-04 US disclosed
US-20160163995-A1 ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2016-06-09 US disclosed
US-20160163995-A1 ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2016-06-09 US disclosed