SCHEMBL16674331

SCHEMBL16674331

c1ccc(-c2ccc(-c3cc(-n4c5ccccc5c5ccc6c7ccccc7n(-c7ccccc7)c6c54)cc(-c4ccc(-c5ccccc5)cc4)n3)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.47
KDM4E B2RXH2 2/20 0.47
ATM Q13315 1/20 0.47
DHODH Q02127 1/20 0.38
KMT2A Q03164 5/20 0.38
IL1R1 P14778 1/20 0.38
MEN1 O00255 4/20 0.37
MAPT P10636 3/20 0.37
ALDH1A1 P00352 3/20 0.37
HTT P42858 1/20 0.37
ACHE P22303 1/20 0.36
AVPR1A P37288 1/20 0.36
CTRC Q99895 1/20 0.35
HSP90AA1 P07900 1/20 0.35
HPGD P15428 2/20 0.35
MAPK1 P28482 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
PTGS2 P35354 1/20 0.35
HDAC4 P56524 1/20 0.34
RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17809192 0.97 KDM4E (0.43) L3MBTL1KDM4EATMDHODHKMT2A
SCHEMBL17809122 0.97 KDM4E (0.43) L3MBTL1KDM4EATMDHODHKMT2A
SCHEMBL10069437 0.97 L3MBTL1 (0.50) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL12131929 0.96 KDM4E (0.50) L3MBTL1KDM4EATMDHODHKMT2A
SCHEMBL10206020 0.96 KDM4E (0.49) L3MBTL1KDM4EATMDHODHKMT2A
SCHEMBL10206015 0.96 L3MBTL1 (0.49) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL15073691 0.94 L3MBTL1 (0.50) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL12131949 0.94 L3MBTL1 (0.44) L3MBTL1KDM4EATMDHODHKMT2A
SCHEMBL17809107 0.93 KDM4E (0.40) L3MBTL1KDM4EATMDHODHKMT2A
SCHEMBL22596349 0.93 L3MBTL1 (0.46) L3MBTL1KDM4EATMDHODHKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3279961-B1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MAT CO LTD (JP) 2023-07-19 EP disclosed
US-20200411772-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2020-12-31 US disclosed
US-10340460-B2 Organic electroluminescent element NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2019-07-02 US disclosed
US-20180083201-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2018-03-22 US disclosed
US-20180083201-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2018-03-22 US disclosed
EP-3279961-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Nippon Steel & Sumikin Chemical Co., Ltd. (JP) 2018-02-07 EP disclosed
US-20150115240-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2015-04-30 US disclosed
US-20150115240-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2015-04-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180083201-A1 ORGANIC ELECTROLUMINESCENT ELEMENT ELF3, LAGE3, ILF3 L3MBTL1 675/4885KDM4E 2186/4885ATM 3581/4885
US-10340460-B2 Organic electroluminescent element EML4, LAGE3, ELOC L3MBTL1 278/4885KDM4E 746/4885ATM 3518/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.