SCHEMBL17810326

SCHEMBL17810326

CCCCc1cc(Cc2ccc(O)c(CCCC)c2)ccc1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 3/20 0.52
BACE1 P56817 1/20 0.49
ESR1 P03372 1/20 0.48
ESR2 Q92731 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA4 P22748 1/20 0.48
CA6 P23280 1/20 0.48
ALOX5 P09917 2/20 0.47
HTT P42858 2/20 0.46
HPGD P15428 2/20 0.46
NPC1 O15118 1/20 0.46
MAPK1 P28482 1/20 0.46
RAB9A P51151 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
CNR1 P21554 1/20 0.46
CNR2 P34972 1/20 0.46
MEN1 O00255 1/20 0.44
TP53 P04637 1/20 0.44
CYP3A4 P08684 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10615007 0.94 TYR (0.51) TYRBACE1ESR1ESR2CA1
SCHEMBL9578492 0.93 TYR (0.46) TYRBACE1ESR1ESR2CA1
SCHEMBL2859174 0.93 TYR (0.54) TYRBACE1ESR1ESR2ALOX5
SCHEMBL10874063 0.93 TYR (0.54) TYRBACE1ESR1ESR2ALOX5
SCHEMBL17810281 0.93 TYR (0.54) TYRBACE1ESR1ESR2ALOX5
SCHEMBL1024663 0.90 HPGD (0.57) TYRBACE1ESR1ALOX5HTT
Phosphine SCHEMBL28136514 0.89 HPGD (0.55) TYRBACE1ESR1ALOX5HTT
SCHEMBL28055345 0.89 HPGD (0.55) TYRBACE1ESR1ALOX5HTT
SCHEMBL165452 0.89 TRPA1 (0.55) TYRBACE1ESR1ESR2ALOX5
SCHEMBL1022454 0.89 ALOX5 (0.60) TYRBACE1ALOX5HTTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9703215-B2 Electrophotographic photoreceptor, method of producing same, and electrophotographic apparatus FUJI ELECTRIC CO., LTD. (JP) 2017-07-11 US disclosed
US-9703215-B2 Electrophotographic photoreceptor, method of producing same, and electrophotographic apparatus FUJI ELECTRIC CO., LTD. (JP) 2017-07-11 US disclosed
US-20160161870-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, METHOD OF PRODUCING SAME, AND ELECTROPHOTOGRAPHIC APPARATUS FUJI ELECTRIC CO., LTD. (JP) 2016-06-09 US disclosed
US-20160161870-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, METHOD OF PRODUCING SAME, AND ELECTROPHOTOGRAPHIC APPARATUS FUJI ELECTRIC CO., LTD. (JP) 2016-06-09 US disclosed