Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 8/20 | 0.60 |
| ▸ | EGFR | P00533 | 3/20 | 0.57 |
| ▸ | LCK | P06239 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 7/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17826399 | 1.00 | CA2 (0.60) | CA2EGFRLCKCA1TSHR | |
| SCHEMBL17810907 | 1.00 | CA2 (0.60) | CA2EGFRLCKCA1TSHR | |
| SCHEMBL7821870 | 0.86 | CA2 (0.62) | CA2EGFRLCKCA1TSHR | |
| SCHEMBL7821874 | 0.86 | CA2 (0.62) | CA2EGFRLCKCA1TSHR | |
| SCHEMBL20334064 | 0.83 | EGFR (0.71) | CA2EGFRLCKCA1TSHR | |
| SCHEMBL9404117 | 0.83 | EGFR (0.71) | CA2EGFRLCKCA1TSHR | |
| SCHEMBL11415394 | 0.82 | CA2 (0.60) | CA2EGFRLCKCA1TSHR | |
| SCHEMBL11415397 | 0.82 | CA2 (0.60) | CA2EGFRLCKCA1TSHR | |
| SCHEMBL11408882 | 0.81 | CA2 (0.54) | CA2EGFRLCKCA1TSHR | |
| SCHEMBL11408885 | 0.81 | CA2 (0.54) | CA2EGFRLCKCA1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9365532-B1 | Synthesis, composition and use of novel therapeutic and cosmetic Schiff base products formed by reaction of a carbonyl containing moeity with a transimination nucleophilic catalyst and the use of transimination nucleophilic catalysts to increase the rate at which carbonyl containing therapeutic and cosmetic actives form Schiff base products with biological amines | Nanometics, LLC. (US) | 2016-06-14 | — | — | US | disclosed |