Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 8/20 | 0.71 |
| ▸ | LCK | P06239 | 1/20 | 0.71 |
| ▸ | CA2 | P00918 | 4/20 | 0.68 |
| ▸ | CA1 | P00915 | 3/20 | 0.68 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | FNTA | P49354 | 1/20 | 0.52 |
| ▸ | FNTB | P49356 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9404117 | 1.00 | EGFR (0.71) | EGFRLCKCA2CA1MAOA | |
| SCHEMBL7821874 | 0.88 | CA2 (0.62) | EGFRLCKCA2CA1MAOB | |
| SCHEMBL7821870 | 0.88 | CA2 (0.62) | EGFRLCKCA2CA1MAOB | |
| SCHEMBL10637996 | 0.85 | ALDH1A1 (0.67) | EGFRLCKCA2CA1MAOB | |
| SCHEMBL7821757 | 0.85 | LMNA (0.67) | EGFRLCKCA2CA1MAOB | |
| SCHEMBL10637987 | 0.85 | ALDH1A1 (0.67) | EGFRLCKCA2CA1MAOB | |
| SCHEMBL7821755 | 0.85 | LMNA (0.67) | EGFRLCKCA2CA1MAOB | |
| SCHEMBL11416448 | 0.85 | EGFR (0.66) | EGFRLCKCA2CA1MAOA | |
| SCHEMBL11416450 | 0.85 | EGFR (0.66) | EGFRLCKCA2CA1MAOA | |
| SCHEMBL17810908 | 0.83 | CA2 (0.60) | EGFRLCKCA2CA1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018116158-A1 | HYDROXYBENZENE DERIVATIVES HAVING A N-ARYL SUBSTITUTE IMINO GROUP AND USE THEREOF IN THE TREATMENT OF SOLID TUMOURS | Università degli Studi di Salerno (IT) | 2018-06-28 | — | — | WO | disclosed |