SCHEMBL1781178

SCHEMBL1781178

CCCCN(CCC[Si](OCC)(OCC)OCC)CCC[Si](OCC)(OCC)OCC

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KDM5A P29375 3/20 0.33
PHF8 Q9UPP1 2/20 0.32
KDM4C Q9H3R0 1/20 0.32
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA9 Q16790 1/20 0.30
HTR1B P28222 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL329699 1.00 KDM5A (0.33) KDM5APHF8KDM4CCA12CA1
SCHEMBL17800744 0.94 DNM1 (0.34) KDM5APHF8KDM4C
SCHEMBL12354589 0.94 DNM1 (0.34) KDM5APHF8KDM4C
SCHEMBL555040 0.93
SCHEMBL5861620 0.92 DNM1 (0.38) KDM5APHF8KDM4CCA12CA1
SCHEMBL18529443 0.92 DNM1 (0.38) KDM5APHF8KDM4CCA12CA1
SCHEMBL8530691 0.92 DNM1 (0.38) KDM5APHF8KDM4CCA12CA1
SCHEMBL17800740 0.92 DNM1 (0.38) KDM5APHF8KDM4CCA12CA1
SCHEMBL4427089 0.91
SCHEMBL1136057 0.91

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12129316-B2 Rubber composition based on a modified diene elastomer COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2024-10-29 US disclosed
US-20210403609-A1 RUBBER COMPOSITION BASED ON A MODIFIED DIENE ELASTOMER COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2021-12-30 US disclosed
US-10072138-B2 Rubber composition for use in tire treads THE YOKOHAMA RUBBER CO., LTD (JP) 2018-09-11 US disclosed
US-9567451-B2 Rubber composition for use in tire treads THE YOKOHAMA RUBBER CO., LTD. (JP) 2017-02-14 US disclosed
US-9493638-B2 Rubber composition for tire THE YOKOHAMA RUBBER CO., LTD. (JP) 2016-11-15 US disclosed
US-9475924-B2 Rubber composition for tire tread and pneumatic tire using the same THE YOKOHAMA RUBBER CO., LTD. (JP) 2016-10-25 US disclosed
US-9416252-B2 Rubber composition for tire tread THE YOKOHAMA RUBBER CO., LTD. (JP) 2016-08-16 US disclosed
US-9139721-B2 Rubber composition for tire treads THE YOKOHAMA RUBBER CO., LTD. (JP) 2015-09-22 US disclosed
US-20150126643-A1 Rubber Composition for Tire THE YOKOHAMA RUBBER CO., LTD. (JP) 2015-05-07 US disclosed
US-20150031791-A1 Rubber Composition for Tire Treads THE YOKOHAMA RUBBER CO., LTD. (JP) 2015-01-29 US disclosed
US-20130338255-A1 RUBBER COMPOSITION FOR TIRE TREAD THE YOKOHAMA RUBBER CO., LTD. (JP) 2013-12-19 US disclosed
US-20130324638-A1 RUBBER COMPOSITION FOR USE IN TIRE TREADS THE YOKOHAMA RUBBER CO., LTD. (JP) 2013-12-05 US disclosed
US-20130267646-A1 RUBBER COMPOSITION FOR TIRE TREAD AND PNEUMATIC TIRE USING THE SAME THE YOKOHAMA RUBBER CO., LTD. (JP) 2013-10-10 US disclosed
EP-2307428-B1 PROCESS FOR PREPARING ALKYLAMINOALKYLALKOXYSILANES EVONIK DEGUSSA GMBH (DE) 2013-07-10 EP disclosed
US-8426628-B2 Process for preparing alkylaminoalkylalkoxysilanes EVONIK DEGUSSA GMBH (DE) 2013-04-23 US disclosed
EP-2003146-B1 USE OF A CONJUGATED DIENE RUBBER FOR A TIRE ZEON CORP (JP) 2012-12-26 EP disclosed
US-20110118496-A1 PROCESS FOR PREPARING ALKYLAMINOALKYLALKOXYSILANES EVONIK DEGUSSA GMBH (DE) 2011-05-19 US disclosed
EP-2003146-A9 CONJUGATED DIENE RUBBER, METHOD FOR PRODUCING THE SAME, RUBBER COMPOSITION FOR TIRE, AND TIRE ZEON CORPORATION (JP) 2009-05-06 EP disclosed
EP-2003146-A2 CONJUGATED DIENE RUBBER, METHOD FOR PRODUCING THE SAME, RUBBER COMPOSITION FOR TIRE, AND TIRE ZEON CORPORATION (JP) 2008-12-17 EP disclosed