Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 3/20 | 0.34 |
| ▸ | KDM5A | P29375 | 3/20 | 0.34 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17800744 | 1.00 | DNM1 (0.34) | DNM1KDM5APHF8KDM4CLMNA | |
| SCHEMBL8530691 | 0.98 | DNM1 (0.38) | DNM1KDM5APHF8KDM4CLMNA | |
| SCHEMBL17800740 | 0.98 | DNM1 (0.38) | DNM1KDM5APHF8KDM4CLMNA | |
| SCHEMBL18529443 | 0.98 | DNM1 (0.38) | DNM1KDM5APHF8KDM4CLMNA | |
| SCHEMBL5861620 | 0.98 | DNM1 (0.38) | DNM1KDM5APHF8KDM4CLMNA | |
| Hydrochloric Acid SCHEMBL1584858 | 0.96 | DNM1 (0.40) | DNM1KDM5APHF8KDM4CLMNA | |
| SCHEMBL329699 | 0.94 | KDM5A (0.33) | KDM5APHF8KDM4C | |
| SCHEMBL1781178 | 0.94 | KDM5A (0.33) | KDM5APHF8KDM4C | |
| Hydrochloric Acid SCHEMBL30605642 | 0.93 | DNM1 (0.38) | DNM1KDM5APHF8KDM4CLMNA | |
| SCHEMBL555040 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8367855-B2 | Process for preparing silylorganoamines | EVONIK DEGUSSA GMBH (DE) | 2013-02-05 | — | — | US | disclosed |
| US-20110201835-A1 | Process for Preparing Silylorganoamines | EVONIK DEGUSSA GMBH (DE) | 2011-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110201835-A1 | Process for Preparing Silylorganoamines | SHROOM3, HRH3, HRH2 | DNM1 3909/4885KDM5A 3094/4885PHF8 3978/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.