Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 13/20 | 0.57 |
| ▸ | FAP | Q12884 | 11/20 | 0.54 |
| ▸ | DPP9 | Q86TI2 | 7/20 | 0.54 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.54 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.54 |
| ▸ | PREP | P48147 | 7/20 | 0.46 |
| ▸ | PITRM1 | Q5JRX3 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3186517 | 0.82 | DPP4 (0.54) | DPP4FAPDPP9DPP8DPP7 | |
| SCHEMBL12709871 | 0.82 | DPP4 (0.50) | DPP4FAPDPP8PREPKMT2A | |
| SCHEMBL6435623 | 0.81 | ALDH1A1 (0.48) | DPP4PREPKMT2AROCK2CYP3A4 | |
| SCHEMBL6435625 | 0.81 | ALDH1A1 (0.48) | DPP4PREPKMT2AROCK2CYP3A4 | |
| SCHEMBL7995565 | 0.79 | DPP4 (0.70) | DPP4FAPDPP8PREP | |
| SCHEMBL7995561 | 0.79 | DPP4 (0.70) | DPP4FAPDPP8PREP | |
| SCHEMBL19334937 | 0.78 | KDM4E (0.53) | DPP4FAPDPP9DPP8DPP7 | |
| SCHEMBL17814191 | 0.78 | KDM4E (0.53) | DPP4FAPDPP9DPP8DPP7 | |
| Hydrochloric Acid SCHEMBL9544338 | 0.76 | DPP4 (0.50) | DPP4PREPKMT2ACYP3A4 | |
| Hydrochloric Acid SCHEMBL9544335 | 0.76 | DPP4 (0.50) | DPP4PREPKMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170333461-A1 | PEPTIDOMIMETIC INHIBITORS OF POST-PROLINE CLEAVING ENZYMES | BACH BIOSCIENCES, LLC | 2017-11-23 | — | — | US | disclosed |
| US-9757400-B2 | Peptidomimetic inhibitors of post-proline cleaving enzymes | TRUSTEES OF TUFTS COLLEGE (US) | 2017-09-12 | — | — | US | disclosed |
| US-20160158260-A1 | Peptidomimetic Inhibitors of Post-Proline Cleaving Enzymes | BACH BIOSCIENCES, LLC | 2016-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170333461-A1 | PEPTIDOMIMETIC INHIBITORS OF POST-PROLINE CLEAVING ENZYMES | PREP, PEPD, DNPEP | DPP4 5/4885FAP 20/4885DPP9 9/4885 |
| US-20160158260-A1 | Peptidomimetic Inhibitors of Post-Proline Cleaving Enzymes | PREP, PEPD, DNPEP | DPP4 5/4885FAP 20/4885DPP9 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.