Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | BRD2 | P25440 | 1/20 | 0.48 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.48 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.48 |
| ▸ | P2RX3 | P56373 | 19/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17814697 | 0.91 | P2RX3 (0.57) | BRD4BRD2BRD3BRDTP2RX3 | |
| SCHEMBL17814695 | 0.90 | P2RX3 (0.56) | BRD4BRD2BRD3BRDTP2RX3 | |
| SCHEMBL17814696 | 0.89 | P2RX3 (0.55) | BRD4BRD2BRD3BRDTP2RX3 | |
| SCHEMBL17814694 | 0.88 | P2RX3 (0.55) | BRD4BRD2BRD3BRDTP2RX3 | |
| SCHEMBL17814745 | 0.87 | P2RX3 (0.58) | P2RX3 | |
| SCHEMBL17814731 | 0.87 | P2RX3 (0.58) | P2RX3 | |
| SCHEMBL17814730 | 0.86 | P2RX3 (0.64) | P2RX3 | |
| SCHEMBL17814744 | 0.86 | P2RX3 (0.51) | BRD4BRD2BRD3BRDTP2RX3 | |
| SCHEMBL17814743 | 0.86 | P2RX3 (0.57) | P2RX3 | |
| SCHEMBL19682684 | 0.85 | P2RX3 (0.55) | P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017209267-A1 | PURINE DERIVATIVE | 塩野義製薬株式会社 | 2017-12-07 | — | — | WO | disclosed |
| WO-2016088838-A1 | PURINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION THEREOF | 塩野義製薬株式会社 | 2016-06-09 | — | — | WO | disclosed |