SCHEMBL17814764

SCHEMBL17814764

CCC(C)(C[C@H]1O[C@@H](c2cn(C)c(=O)[nH]c2=O)[C@H](O)[C@@H]1O)OP(=O)(O)[C@H](C)O

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
DNPH1 O43598 1/20 0.33
UMPS P11172 1/20 0.33
P2RY6 Q15077 10/20 0.32
EIF4E P06730 2/20 0.32
P2RY14 Q15391 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15764141 1.00 DNPH1 (0.33) DNPH1UMPSP2RY6EIF4EP2RY14
SCHEMBL16597025 1.00 DNPH1 (0.33) DNPH1UMPSP2RY6EIF4EP2RY14
SCHEMBL16479392 1.00 DNPH1 (0.33) DNPH1UMPSP2RY6EIF4EP2RY14
SCHEMBL17703443 0.93 DNPH1 (0.33) DNPH1UMPSP2RY6EIF4EP2RY14
SCHEMBL17277059 0.89 P2RY6 (0.33) DNPH1UMPSP2RY6EIF4EP2RY14
SCHEMBL14930934 0.88 DNPH1 (0.34) DNPH1UMPSP2RY6EIF4EP2RY14
SCHEMBL18844822 0.87 P2RY6 (0.34) DNPH1UMPSP2RY6EIF4EP2RY14
SCHEMBL14948855 0.87 DNPH1 (0.33) DNPH1UMPSP2RY6EIF4EP2RY14
SCHEMBL15870442 0.87 P2RY6 (0.34) DNPH1UMPSP2RY6EIF4EP2RY14
SCHEMBL15250721 0.87 P2RY6 (0.34) DNPH1UMPSP2RY6EIF4EP2RY14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160158385-A1 MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF CYTOPLASMIC AND CYTOSKELETAL PROTEINS ARES CAPITAL CORPORATION, AS AGENT 2016-06-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160158385-A1 MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF CYTOPLASMIC AND CYTOSKELETAL PROTEINS POLRMT, POLN, PHAX DNPH1 3443/4885UMPS 1052/4885P2RY6 3989/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.