Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 4/20 | 0.63 |
| ▸ | HDAC3 | O15379 | 15/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 15/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 15/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 15/20 | 0.61 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17814776 | 0.80 | HDAC3 (0.60) | VNN1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL20491534 | 0.80 | VNN1 (0.78) | VNN1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL18742508 | 0.78 | HDAC3 (0.78) | VNN1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL19710840 | 0.77 | VNN1 (0.61) | VNN1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL21180512 | 0.77 | VNN1 (0.66) | VNN1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL18286325 | 0.77 | VNN1 (1.00) | VNN1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL4730434 | 0.76 | HDAC3 (1.00) | VNN1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL17813775 | 0.76 | HDAC3 (0.71) | VNN1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL18769528 | 0.75 | VNN1 (0.59) | VNN1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL20491187 | 0.74 | HDAC6 (0.64) | VNN1HDAC3HDAC1HDAC2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016087950-A1 | COMBINATIONS OF HISTONE DEACETYLASE INHIBITORS AND BENDAMUSTINE FOR USE IN THE TREATMENT OF LYMPHOMA | University of Modena and Reggio Emilia (IT) | 2016-06-09 | — | — | WO | disclosed |