Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 15/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 15/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 15/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 15/20 | 0.60 |
| ▸ | VNN1 | O95497 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18822437 | 0.82 | HDAC3 (0.89) | HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL17814775 | 0.80 | VNN1 (0.63) | HDAC3HDAC1HDAC2HDAC6VNN1 | |
| SCHEMBL18742678 | 0.80 | HDAC3 (0.73) | HDAC3HDAC1HDAC2HDAC6VNN1 | |
| SCHEMBL18742506 | 0.76 | HDAC3 (0.64) | HDAC3HDAC1HDAC2HDAC6VNN1 | |
| SCHEMBL4729826 | 0.75 | HDAC3 (1.00) | HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL19710705 | 0.73 | HDAC6 (0.67) | HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL18742679 | 0.72 | HDAC3 (0.66) | HDAC3HDAC1HDAC2HDAC6VNN1 | |
| SCHEMBL18742613 | 0.72 | HDAC3 (0.66) | HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL28067236 | 0.70 | HDAC3 (0.79) | HDAC3HDAC1HDAC2HDAC6VNN1 | |
| SCHEMBL24968663 | 0.69 | HDAC3 (0.53) | HDAC3HDAC1HDAC2HDAC6VNN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016087950-A1 | COMBINATIONS OF HISTONE DEACETYLASE INHIBITORS AND BENDAMUSTINE FOR USE IN THE TREATMENT OF LYMPHOMA | University of Modena and Reggio Emilia (IT) | 2016-06-09 | — | — | WO | disclosed |