Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12608099 | 0.92 | KDM4E (0.48) | KDM4EALDH1A1HPGDMAPTTDP1 | |
| SCHEMBL1445183 | 0.86 | MIF (0.52) | KDM4EALDH1A1HPGDMAPTTDP1 | |
| SCHEMBL1445236 | 0.86 | KDM4E (0.47) | KDM4EALDH1A1HPGDMAPTTDP1 | |
| SCHEMBL4828368 | 0.86 | KDM4E (0.47) | KDM4EALDH1A1HPGDMAPTTDP1 | |
| SCHEMBL13966932 | 0.79 | KDM4E (0.42) | KDM4EALDH1A1HPGDMAPTTDP1 | |
| SCHEMBL13409312 | 0.78 | KDM4E (0.40) | KDM4EALDH1A1HPGDMAPTTDP1 | |
| SCHEMBL11785156 | 0.78 | KMT2A (0.57) | KDM4EALDH1A1HPGDMAPTTDP1 | |
| SCHEMBL7536729 | 0.78 | SMN1; SMN2 (0.62) | KDM4EALDH1A1HPGDMAPTTDP1 | |
| SCHEMBL1445882 | 0.77 | KDM4E (0.53) | KDM4EALDH1A1HPGDMAPTTDP1 | |
| SCHEMBL21127191 | 0.77 | KDM4E (0.50) | KDM4EALDH1A1HPGDMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110118483-A1 | n-Type thiophene semiconductors | POLYERA CORPORATION | 2011-05-19 | — | — | US | disclosed |
| US-7842198-B2 | n-Type thiophene semiconductors | NORTHWESTERN UNIVERSITY (US) | 2010-11-30 | — | — | US | disclosed |
| US-20080293937-A1 | n-Type Thiophene Semiconductors | POLYERA CORPORATION | 2008-11-27 | — | — | US | disclosed |
| US-7374702-B2 | n-Type thiophene semiconductors | NORTHWESTERN UNIVERSITY (US) | 2008-05-20 | — | — | US | disclosed |
| US-20060124909-A1 | n-Type thiophene semiconductors | POLYERA CORPORATION | 2006-06-15 | — | — | US | disclosed |
| US-6991749-B2 | n-Type thiophene semiconductors | NORTHWESTERN UNIVERSITY (US) | 2006-01-31 | — | — | US | disclosed |
| US-20050119440-A1 | n-Type thiophene semiconductors | NATIONAL SCIENCE FOUNDATION | 2005-06-02 | — | — | US | disclosed |
| US-6585914-B2 | N-type thiophene semiconductors | NORTHWESTERN UNIVERSITY | 2003-07-01 | — | — | US | disclosed |
| US-20030080324-A1 | n-type thiophene semiconductors | NORTHWESTERN UNIVERSITY | 2003-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293937-A1 | n-Type Thiophene Semiconductors | FTH1, FECH, CD2 | KDM4E 628/4885ALDH1A1 2700/4885HPGD 4550/4885 |
| US-20110118483-A1 | n-Type thiophene semiconductors | FTH1, FECH, CD2 | KDM4E 628/4885ALDH1A1 2700/4885HPGD 4550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.