Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.62 |
| ▸ | NPC1 | O15118 | 6/20 | 0.62 |
| ▸ | RAB9A | P51151 | 6/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1781579 | 0.78 | KDM4E (0.56) | SMN1; SMN2NPC1RAB9ACYP1A2CYP2C9 | |
| SCHEMBL22063717 | 0.77 | SMN1; SMN2 (1.00) | SMN1; SMN2NPC1RAB9ACYP1A2CYP2C9 | |
| SCHEMBL13966932 | 0.77 | KDM4E (0.42) | SMN1; SMN2NPC1RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL8217612 | 0.76 | SMN1; SMN2 (0.71) | SMN1; SMN2NPC1RAB9ACYP1A2CYP2C9 | |
| SCHEMBL13409312 | 0.76 | KDM4E (0.40) | SMN1; SMN2NPC1RAB9ACYP1A2CYP2C9 | |
| SCHEMBL27732880 | 0.76 | ASIC3 (0.55) | SMN1; SMN2NPC1RAB9ACYP1A2CYP2C9 | |
| SCHEMBL557685 | 0.72 | NPC1 (0.61) | SMN1; SMN2NPC1RAB9ACYP1A2CYP2C9 | |
| SCHEMBL12608099 | 0.72 | KDM4E (0.48) | SMN1; SMN2NPC1RAB9ACYP1A2CYP2C9 | |
| SCHEMBL13942151 | 0.71 | IDO1 (0.36) | SMN1; SMN2NPC1RAB9ACYP1A2CYP2C9 | |
| SCHEMBL1445236 | 0.70 | KDM4E (0.47) | SMN1; SMN2NPC1RAB9ACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0819690-B1 | Herbicidal 6-thienyl and 4-thienyl pyrimidines | BASF AG (DE) | 2002-10-09 | — | — | EP | disclosed |