Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | LPL | P06858 | 7/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 7/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL875957 | 0.87 | FFAR1 (0.51) | FFAR1LPLLIPGIRAK4ESR2 | |
| SCHEMBL19713715 | 0.85 | FFAR1 (0.50) | FFAR1LPLLIPGIRAK4ESR2 | |
| SCHEMBL17815970 | 0.85 | FFAR1 (0.50) | FFAR1LPLLIPGIRAK4ESR2 | |
| SCHEMBL17005480 | 0.84 | FFAR1 (0.52) | FFAR1LPLLIPGIRAK4ESR2 | |
| SCHEMBL30291377 | 0.83 | FFAR1 (0.51) | FFAR1LPLLIPGIRAK4 | |
| SCHEMBL1989062 | 0.82 | FFAR1 (0.50) | FFAR1LPLLIPGIRAK4ESR2 | |
| SCHEMBL17815962 | 0.81 | FFAR1 (0.50) | FFAR1LPLLIPGIRAK4 | |
| SCHEMBL17815961 | 0.81 | FFAR1 (0.50) | FFAR1LPLLIPGIRAK4 | |
| SCHEMBL17815960 | 0.81 | FFAR1 (0.50) | FFAR1LPLLIPGIRAK4 | |
| SCHEMBL22527457 | 0.80 | FFAR1 (0.52) | FFAR1LPLLIPGIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016090285-A1 | 4,6-SUBSTITUTED-PYRAZOLO[1,5-a]PYRAZINES AS JANUS KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2016-06-09 | — | — | WO | disclosed |