SCHEMBL1989062

SCHEMBL1989062

CC1(C)OB(c2cnn(C(F)F)c2)OC1(C)C

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.50
LPL P06858 12/20 0.38
LIPG Q9Y5X9 12/20 0.38
IRAK4 Q9NWZ3 1/20 0.33
AAK1 Q2M2I8 1/20 0.33
ESR2 Q92731 1/20 0.31
CA1 P00915 2/20 0.30
CA2 P00918 2/20 0.30
CA9 Q16790 2/20 0.30
CA12 O43570 1/20 0.30
CA3 P07451 1/20 0.30
CA4 P22748 1/20 0.30
CA6 P23280 1/20 0.30
CA5A P35218 1/20 0.30
CA7 P43166 1/20 0.30
CA14 Q9ULX7 1/20 0.30
CA5B Q9Y2D0 1/20 0.30
LRRK2 Q5S007 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28975944 0.87 FFAR1 (0.48) FFAR1LPLLIPGIRAK4AAK1
SCHEMBL875957 0.85 FFAR1 (0.51) FFAR1LPLLIPGIRAK4ESR2
SCHEMBL22443079 0.84 FFAR1 (0.37) FFAR1
SCHEMBL17815970 0.83 FFAR1 (0.50) FFAR1LPLLIPGIRAK4AAK1
SCHEMBL19713715 0.83 FFAR1 (0.50) FFAR1LPLLIPGIRAK4AAK1
SCHEMBL15416423 0.83 FFAR1 (0.50) FFAR1LPLLIPGIRAK4AAK1
SCHEMBL29171601 0.82 FFAR1 (0.47) FFAR1LPLLIPGIRAK4AAK1
SCHEMBL20400272 0.82 LIPG (0.53) FFAR1LPLLIPGESR2CA1
SCHEMBL17815976 0.82 FFAR1 (0.49) FFAR1LPLLIPGIRAK4AAK1
SCHEMBL17005480 0.82 FFAR1 (0.52) FFAR1LPLLIPGIRAK4AAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 810 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260132139-A1 HIV INHIBITOR COMPOUNDS GILEAD SCIENCES INC (US) 2026-05-14 US disclosed
EP-4737443-A1 SALT-INDUCIBLE KINASE INHIBITORY COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING SAME Tanabe Pharma Corporation (JP) 2026-05-06 EP disclosed
EP-4727540-A2 FUSED BICYCLIC HETEROCYCLIC OR HETERO ARYL AMIDE COMPOUNDS Quantx Biosciences US, Inc. (US) 2026-04-22 EP disclosed
US-20260098036-A1 2-HETEROARYL-3-OXO-2,3-DIHYDROPYRIDAZINE-4-CARBOXAMIDES FOR THE TREATMENT OF CANCER DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) 2026-04-09 US disclosed
US-20260092053-A1 KHK INHIBITORS GILEAD SCIENCES INC (US) 2026-04-02 US disclosed
EP-3710428-B1 MODULATORS OF THE INTEGRATED STRESS PATHWAY CALICO LIFE SCIENCES LLC (US) 2026-03-25 EP disclosed
US-20260078103-A1 ISOQUINOLONES AS PI3K INHIBITORS ONKURE, INC. (US) 2026-03-19 US disclosed
US-12581252-B2 Substituted pyrrolo[3,4-b]pyridines as PI3K-α inhibitors RELAY THERAPEUTICS, INC. (US) 2026-03-17 US disclosed
EP-4271674-B9 CARBOXY-BENZIMIDAZOLE GLP-1R MODULATING COMPOUNDS GILEAD SCIENCES INC (US) 2026-03-11 EP disclosed
US-12570642-B2 GLP-IR modulating compounds GILEAD SCIENCES, INC. (US) 2026-03-10 US disclosed
US-20120028951-A1 PYRIDAZINONE COMPOUNDS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2012-02-02 US disclosed
WO-2011079051-A1 FUSED HETEROAROMATIC PYRROLIDINONES AS SYK INHIBITORS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2011-06-30 WO disclosed
WO-2011079051-A1 FUSED HETEROAROMATIC PYRROLIDINONES AS SYK INHIBITORS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2011-06-30 WO disclosed
US-20110152273-A1 FUSED HETEROAROMATIC PYRROLIDINONES TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2011-06-23 US disclosed
US-20110152273-A1 FUSED HETEROAROMATIC PYRROLIDINONES TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2011-06-23 US disclosed
US-20110152273-A1 FUSED HETEROAROMATIC PYRROLIDINONES TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2011-06-23 US disclosed
US-20100197651-A1 Pyridazinone compounds TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2010-08-05 US disclosed
US-20100197651-A1 Pyridazinone compounds TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2010-08-05 US disclosed
WO-2010010184-A1 [1, 2, 4] TRIAZOLO [1, 5-A] PYRIDINES AS JAK INHIBITORS GALAPAGOS NV (BE) 2010-01-28 WO disclosed
WO-2010010184-A1 [1, 2, 4] TRIAZOLO [1, 5-A] PYRIDINES AS JAK INHIBITORS GALAPAGOS NV (BE) 2010-01-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260098036-A1 2-HETEROARYL-3-OXO-2,3-DIHYDROPYRIDAZINE-4-CARBOXAMIDES FOR THE TREATMENT OF CANCER AHR, CBR1, CNR1 FFAR1 125/4885LPL 4105/4885LIPG 3906/4885
US-20260092053-A1 KHK INHIBITORS KHK, SLC5A2, HK1 FFAR1 180/4885LPL 178/4885LIPG 249/4885
US-20110152273-A1 FUSED HETEROAROMATIC PYRROLIDINONES SYK, ZAP70, LYN FFAR1 1357/4885LPL 4118/4885LIPG 1619/4885
US-20120028951-A1 PYRIDAZINONE COMPOUNDS PDE3A, PDE5A, PDE3B FFAR1 2728/4885LPL 869/4885LIPG 3057/4885
US-20100197651-A1 Pyridazinone compounds PDE3A, PDE5A, PDE3B FFAR1 2699/4885LPL 851/4885LIPG 3040/4885
US-20260132139-A1 HIV INHIBITOR COMPOUNDS SLC11A2, SLC6A15, NHERF1 FFAR1 3877/4885LPL 4064/4885LIPG 1943/4885
US-20260078103-A1 ISOQUINOLONES AS PI3K INHIBITORS PIK3R5, PIK3R4, PIK3CA FFAR1 412/4885LPL 533/4885LIPG 2181/4885
US-12581252-B2 Substituted pyrrolo[3,4-b]pyridines as PI3K-α inhibitors RORB, ROR1, RORA FFAR1 313/4885LPL 2360/4885LIPG 3692/4885
US-12570642-B2 GLP-IR modulating compounds GLP1R, GIPR, GPR119 FFAR1 67/4885LPL 186/4885LIPG 245/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.